Reprogramming competence of OCT factors is determined by transactivation domains

OCT4 (also known as POU5F1) plays an essential role in reprogramming. It is the only member of the POU (Pit-Oct-Unc) family of transcription factors that can induce pluripotency despite sharing high structural similarities to all other members. Here, we discover that OCT6 (also known as POU3F1) can...

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Udgivet i:Sci Adv
Main Authors: Kim, Kee-Pyo, Wu, You, Yoon, Juyong, Adachi, Kenjiro, Wu, Guangming, Velychko, Sergiy, MacCarthy, Caitlin M., Shin, Borami, Röpke, Albrecht, Arauzo-Bravo, Marcos J., Stehling, Martin, Han, Dong Wook, Gao, Yawei, Kim, Johnny, Gao, Shaorong, Schöler, Hans R.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467702/
https://ncbi.nlm.nih.gov/pubmed/32917606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz7364
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