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Metastable Reprogramming State of Single Transcription Factor-Derived Induced Hepatocyte-Like Cells

We previously described the generation of induced hepatocyte-like cells (iHeps) using the hepatic transcription factor Hnf1a together with small molecules. These iHeps represent a hepatic state that is more mature compared with iHeps generated with multiple hepatic factors. However, the underlying m...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Hwang, Seon In, Kwak, Tae Hwan, Kang, Ji Hyun, Kim, Jonghun, Lee, Hyunseong, Kim, Kee-Pyo, Ko, Kinarm, Schöler, Hans R., Han, Dong Wook
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476006/
https://ncbi.nlm.nih.gov/pubmed/31089332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6937257
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