Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis

BACKGROUND: Organic cation transporters (OCT) are responsible for the uptake of a broad spectrum of endogenous and exogenous substrates. Downregulation of OCT is frequently observed in human hepatocellular carcinoma (HCC) and is associated with a poor outcome. The aim of our current study was to elu...

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Publicat a:Oncotarget
Autors principals: Vollmar, Johanna, Lautem, Anja, Closs, Ellen, Schuppan, Detlef, Kim, Yong Ook, Grimm, Daniel, Marquardt, Jens U., Fuchs, Peter, Straub, Beate K., Schad, Arno, Gründemann, Dirk, Schattenberg, Jörn M., Gehrke, Nadine, Wörns, Marcus A., Baumgart, Jan, Galle, Peter R., Zimmermann, Tim
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777802/
https://ncbi.nlm.nih.gov/pubmed/29383190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23372
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