Methylomes of renal cell lines and tumors or metastases differ significantly with impact on pharmacogenes

Current therapies for metastatic clear cell renal cell carcinoma (ccRCC) show limited efficacy. Drug efficacy, typically investigated in preclinical cell line models during drug development, is influenced by pharmacogenes involved in targeting and disposition of drugs. Here we show through genome-wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Winter, Stefan, Fisel, Pascale, Büttner, Florian, Rausch, Steffen, D’Amico, Debora, Hennenlotter, Jörg, Kruck, Stephan, Nies, Anne T., Stenzl, Arnulf, Junker, Kerstin, Scharpf, Marcus, Hofmann, Ute, van der Kuip, Heiko, Fend, Falko, Ott, German, Agaimy, Abbas, Hartmann, Arndt, Bedke, Jens, Schwab, Matthias, Schaeffeler, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951699/
https://ncbi.nlm.nih.gov/pubmed/27435027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29930
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados