Curtailing side effects in chemotherapy: a tale of PKCδ in cisplatin treatment

par Pabla, Navjotsingh, Dong, Zheng
Publié 2012

CCR 20(th) Anniversary Commentary: BMS-247550—Microtubule Stabilization as Successful Targeted Therapy

par Pabla, Navjotsingh, Sparreboom, Alex
Publié dans Clin Cancer Res (2015)

Checkpoint kinase 1 (Chk1)-short is a splice variant and endogenous inhibitor of Chk1 that regulates cell cycle and DNA damage checkpoints

par Pabla, Navjotsingh, Bhatt, Kirti, Dong, Zheng
Publié 2012

Checkpoint kinase 1 in DNA damage response and cell cycle regulation

par Patil, Mallikarjun, Pabla, Navjotsingh, Dong, Zheng
Publié 2013

Nek1 phosphorylates Von Hippel-Lindau tumor suppressor to promote its proteasomal degradation and ciliary destabilization

par Patil, Mallikarjun, Pabla, Navjotsingh, Huang, Shuang, Dong, Zheng
Publié 2013

The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

par Pabla, Navjotsingh, Murphy, Robert F., Liu, Kebin, Dong, Zheng
Publié 2009

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

par Patil, Mallikarjun, Pabla, Navjotsingh, Ding, Han-Fei, Dong, Zheng
Publié 2013

DNA Damage Response in Cisplatin-Induced Nephrotoxicity

par Zhu, Shiyao, Pabla, Navjotsingh, Tang, Chengyuan, He, Liyu, Dong, Zheng
Publié dans Arch Toxicol (2015)

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. VOLUME 283 (2008) PAGES 6572-6583

par Pabla, Navjotsingh, Huang, Shuang, Mi, Qing-Sheng, Daniel, Rene, Dong, Zheng
Publié 2008

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

par Pabla, Navjotsingh, Ma, Zhengwei, McIlhatton, Michael A., Fishel, Richard, Dong, Zheng
Publié 2011

PKC-δ Promotes Renal Tubular Cell Apoptosis Associated with Proteinuria

par Li, Xiaoning, Pabla, Navjotsingh, Wei, Qingqing, Dong, Guie, Messing, Robert O., Wang, Cong-Yi, Dong, Zheng
Publié 2010

Inhibition of PKCδ reduces cisplatin-induced nephrotoxicity without blocking chemotherapeutic efficacy in mouse models of cancer

par Pabla, Navjotsingh, Dong, Guie, Jiang, Man, Huang, Shuang, Kumar, M. Vijay, Messing, Robert O., Dong, Zheng
Publié 2011

MicroRNA-687 Induced by Hypoxia-Inducible Factor-1 Targets Phosphatase and Tensin Homolog in Renal Ischemia-Reperfusion Injury

par Bhatt, Kirti, Wei, Qingqing, Pabla, Navjotsingh, Dong, Guie, Mi, Qing-Sheng, Liang, Mingyu, Mei, Changlin, Dong, Zheng
Publié dans J Am Soc Nephrol (2015)

Cisplatin-Induced Renal Injury is Independently Mediated by OCT2 and p53

par Sprowl, Sprowl, Lancaster, Cynthia S., Pabla, Navjotsingh, Hermann, Edwin, Kosloske, Ashley M., Gibson, Alice A., Li, Lie, Zeeh, Dorothea, Schlatter, Eberhard, Janke, Laura J., Ciarimboli, Giuliano, Sparreboom, Alex
Publié 2014

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

par Pabla, Navjotsingh, Gibson, Alice A., Buege, Mike, Ong, Su Sien, Li, Lie, Hu, Shuiying, Du, Guoqing, Sprowl, Jason A., Vasilyeva, Aksana, Janke, Laura J., Schlatter, Eberhard, Chen, Taosheng, Ciarimboli, Giuliano, Sparreboom, Alex
Publié dans Proc Natl Acad Sci U S A (2015)

OCTN1 is a high-affinity carrier of nucleoside analogs

par Drenberg, Christina D., Gibson, Alice A., Pounds, Stanley B., Shi, Lei, Rhinehart, Dena P., Li, Lie, Hu, Shuiying, Du, Guoqing, Nies, Anne T., Schwab, Matthias, Pabla, Navjotsingh, Blum, William, Gruber, Tanja A., Baker, Sharyn D., Sparreboom, Alex
Publié dans Cancer Res (2017)

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia

par van Oosterwijk, Jolieke G., Buelow, Daelynn R., Drenberg, Christina D., Vasilyeva, Aksana, Li, Lie, Shi, Lei, Wang, Yong-Dong, Finkelstein, David, Shurtleff, Sheila A., Janke, Laura J., Pounds, Stanley, Rubnitz, Jeffrey E., Inaba, Hiroto, Pabla, Navjotsingh, Baker, Sharyn D.
Publié dans J Clin Invest (2017)

A phosphotyrosine switch regulates organic cation transporters

par Sprowl, Jason A., Ong, Su Sien, Gibson, Alice A., Hu, Shuiying, Du, Guoqing, Lin, Wenwei, Li, Lie, Bharill, Shashank, Ness, Rachel A., Stecula, Adrian, Offer, Steven M., Diasio, Robert B., Nies, Anne T., Schwab, Matthias, Cavaletti, Guido, Schlatter, Eberhard, Ciarimboli, Giuliano, Schellens, Jan H. M., Isacoff, Ehud Y., Sali, Andrej, Chen, Taosheng, Baker, Sharyn D., Sparreboom, Alex, Pabla, Navjotsingh
Publié dans Nat Commun (2016)