A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging

ανά Su, Jing, Ekman, Carl, Oskolkov, Nikolay, Lahti, Leo, Ström, Kristoffer, Brazma, Alvis, Groop, Leif, Rung, Johan, Hansson, Ola
Τόπος έκδοσης Skelet Muscle (2015)

Myocardin Family Members Drive Formation of Caveolae

ανά Krawczyk, Katarzyna K., Yao Mattisson, Ingrid, Ekman, Mari, Oskolkov, Nikolay, Grantinge, Rebecka, Kotowska, Dorota, Olde, Björn, Hansson, Ola, Albinsson, Sebastian, Miano, Joseph M., Rippe, Catarina, Swärd, Karl
Τόπος έκδοσης PLoS One (2015)

Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

ανά Bartoschek, Michael, Oskolkov, Nikolay, Bocci, Matteo, Lövrot, John, Larsson, Christer, Sommarin, Mikael, Madsen, Chris D., Lindgren, David, Pekar, Gyula, Karlsson, Göran, Ringnér, Markus, Bergh, Jonas, Björklund, Åsa, Pietras, Kristian
Τόπος έκδοσης Nat Commun (2018)

TCF7L2 is a master regulator of insulin production and processing

ανά Zhou, Yuedan, Park, Soo-Young, Su, Jing, Bailey, Kathleen, Ottosson-Laakso, Emilia, Shcherbina, Liliya, Oskolkov, Nikolay, Zhang, Enming, Thevenin, Thomas, Fadista, João, Bennet, Hedvig, Vikman, Petter, Wierup, Nils, Fex, Malin, Rung, Johan, Wollheim, Claes, Nobrega, Marcelo, Renström, Erik, Groop, Leif, Hansson, Ola
Τόπος έκδοσης Hum Mol Genet (2014)

Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia

ανά Halvorsen, Matthew, Huh, Ruth, Oskolkov, Nikolay, Wen, Jia, Netotea, Sergiu, Giusti-Rodriguez, Paola, Karlsson, Robert, Bryois, Julien, Nystedt, Björn, Ameur, Adam, Kähler, Anna K., Ancalade, NaEshia, Farrell, Martilias, Crowley, James J., Li, Yun, Magnusson, Patrik K. E., Gyllensten, Ulf, Hultman, Christina M., Sullivan, Patrick F., Szatkiewicz, Jin P.
Τόπος έκδοσης Nat Commun (2020)

N(1)-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism

ανά Ström, Kristoffer, Morales-Alamo, David, Ottosson, Filip, Edlund, Anna, Hjort, Line, Jörgensen, Sine W., Almgren, Peter, Zhou, Yuedan, Martin-Rincon, Marcos, Ekman, Carl, Pérez-López, Alberto, Ekström, Ola, Perez-Suarez, Ismael, Mattiasson, Markus, de Pablos-Velasco, Pedro, Oskolkov, Nikolay, Ahlqvist, Emma, Wierup, Nils, Eliasson, Lena, Vaag, Allan, Groop, Leif, Stenkula, Karin G., Fernandez, Céline, Calbet, Jose A. L., Holmberg, Hans-Christer, Hansson, Ola
Τόπος έκδοσης Sci Rep (2018)

Genetic Predisposition for Beta Cell Fragility Underlies Type 1 and Type 2 Diabetes

ανά Dooley, James, Tian, Lei, Schonefeldt, Susann, Delghingaro-Augusto, Viviane, Garcia-Perez, Josselyn E, Pasciuto, Emanuela, Di Marino, Daniele, Carr, Edward J, Oskolkov, Nikolay, Lyssenko, Valeriya, Franckaert, Dean, Lagou, Vasiliki, Overbergh, Lut, Vandenbussche, Jonathan, Allemeersch, Joke, Chabot-Roy, Genevieve, Dahlstrom, Jane E, Laybutt, D Ross, Petrovsky, Nikolai, Socha, Luis, Gevaert, Kris, Jetten, Anton M, Lambrechts, Diether, Linterman, Michelle A, Goodnow, Chris C, Nolan, Christopher J, Lesage, Sylvie, Schlenner, Susan M, Liston, Adrian
Τόπος έκδοσης Nat Genet (2016)

Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms

ανά Claussnitzer, Melina, Dankel, Simon N., Klocke, Bernward, Grallert, Harald, Glunk, Viktoria, Berulava, Tea, Lee, Heekyoung, Oskolkov, Nikolay, Fadista, Joao, Ehlers, Kerstin, Wahl, Simone, Hoffmann, Christoph, Qian, Kun, Rönn, Tina, Riess, Helene, Müller-Nurasyid, Martina, Bretschneider, Nancy, Schroeder, Timm, Skurk, Thomas, Horsthemke, Bernhard, Spieler, Derek, Klingenspor, Martin, Seifert, Martin, Kern, Michael J., Mejhert, Niklas, Dahlman, Ingrid, Hansson, Ola, Hauck, Stefanie M., Blüher, Matthias, Arner, Peter, Groop, Leif, Illig, Thomas, Suhre, Karsten, Hsu, Yi-Hsiang, Mellgren, Gunnar, Hauner, Hans, Laumen, Helmut
Τόπος έκδοσης Cell (2014)

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes

ανά Peiris, Heshan, Duffield, Michael D., Fadista, Joao, Jessup, Claire F., Kashmir, Vinder, Genders, Amanda J., McGee, Sean L., Martin, Alyce M., Saiedi, Madiha, Morton, Nicholas, Carter, Roderick, Cousin, Michael A., Kokotos, Alexandros C., Oskolkov, Nikolay, Volkov, Petr, Hough, Tertius A., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Busciglio, Jorge, Coskun, Pinar E., Becker, Ann, Belichenko, Pavel V., Mobley, William C., Ryan, Michael T., Chan, Jeng Yie, Laybutt, D. Ross, Coates, P. Toby, Yang, Sijun, Ling, Charlotte, Groop, Leif, Pritchard, Melanie A., Keating, Damien J.
Τόπος έκδοσης PLoS Genet (2016)

Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D

ανά Viñuela, Ana, Varshney, Arushi, van de Bunt, Martijn, Prasad, Rashmi B., Asplund, Olof, Bennett, Amanda, Boehnke, Michael, Brown, Andrew A., Erdos, Michael R., Fadista, João, Hansson, Ola, Hatem, Gad, Howald, Cédric, Iyengar, Apoorva K., Johnson, Paul, Krus, Ulrika, MacDonald, Patrick E., Mahajan, Anubha, Manning Fox, Jocelyn E., Narisu, Narisu, Nylander, Vibe, Orchard, Peter, Oskolkov, Nikolay, Panousis, Nikolaos I., Payne, Anthony, Stitzel, Michael L., Vadlamudi, Swarooparani, Welch, Ryan, Collins, Francis S., Mohlke, Karen L., Gloyn, Anna L., Scott, Laura J., Dermitzakis, Emmanouil T., Groop, Leif, Parker, Stephen C. J., McCarthy, Mark I.
Τόπος έκδοσης Nat Commun (2020)

The Genetic Landscape of Renal Complications in Type 1 Diabetes

ανά Sandholm, Niina, Van Zuydam, Natalie, Ahlqvist, Emma, Juliusdottir, Thorhildur, Deshmukh, Harshal A., Rayner, N. William, Di Camillo, Barbara, Forsblom, Carol, Fadista, Joao, Ziemek, Daniel, Salem, Rany M., Hiraki, Linda T., Pezzolesi, Marcus, Trégouët, David, Dahlström, Emma, Valo, Erkka, Oskolkov, Nikolay, Ladenvall, Claes, Marcovecchio, M. Loredana, Cooper, Jason, Sambo, Francesco, Malovini, Alberto, Manfrini, Marco, McKnight, Amy Jayne, Lajer, Maria, Harjutsalo, Valma, Gordin, Daniel, Parkkonen, Maija, Lyssenko, Valeriya, McKeigue, Paul M., Rich, Stephen S., Brosnan, Mary Julia, Fauman, Eric, Bellazzi, Riccardo, Rossing, Peter, Hadjadj, Samy, Krolewski, Andrzej, Paterson, Andrew D., Hirschhorn, Joel N., Maxwell, Alexander P., Cobelli, Claudio, Colhoun, Helen M., Groop, Leif, McCarthy, Mark I., Groop, Per-Henrik
Τόπος έκδοσης J Am Soc Nephrol (2017)

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

ανά Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben, Brage, Søren, Cheng, Yu-Ching, Cięszczyk, Paweł, Derave, Wim, Eriksson, Karl-Fredrik, Eynon, Nir, Linneberg, Allan, Lucia, Alejandro, Massidda, Myosotis, Mitchell, Braxton D., Miyachi, Motohiko, Murakami, Haruka, Padmanabhan, Sandosh, Pandey, Ashutosh, Papadimitriou, Ioannis, Rajpal, Deepak K., Sale, Craig, Schnurr, Theresia M., Sessa, Francesco, Shrine, Nick, Tobin, Martin D., Varley, Ian, Wain, Louise V., Wray, Naomi R., Lindgren, Cecilia M., MacArthur, Daniel G., Waterworth, Dawn M., McCarthy, Mark I., Pedersen, Oluf, Khaw, Kay-Tee, Kiel, Douglas P., Pitsiladis, Yannis, Fuku, Noriyuki, Franks, Paul W., North, Kathryn N., van Duijn, Cornelia M., Mather, Karen A., Hansen, Torben, Hansson, Ola, Spector, Tim, Murabito, Joanne M., Richards, J. Brent, Rivadeneira, Fernando, Langenberg, Claudia, Perry, John R. B., Wareham, Nick J., Scott, Robert A.
Τόπος έκδοσης Nat Commun (2017)

Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

ανά Gaulton, Kyle J, Ferreira, Teresa, Lee, Yeji, Raimondo, Anne, Mägi, Reedik, Reschen, Michael E, Mahajan, Anubha, Locke, Adam, Rayner, N William, Robertson, Neil, Scott, Robert A, Prokopenko, Inga, Scott, Laura J, Green, Todd, Sparso, Thomas, Thuillier, Dorothee, Yengo, Loic, Grallert, Harald, Wahl, Simone, Frånberg, Mattias, Strawbridge, Rona J, Kestler, Hans, Chheda, Himanshu, Eisele, Lewin, Gustafsson, Stefan, Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Qi, Lu, Karssen, Lennart C, van Leeuwen, Elisabeth M, Willems, Sara M, Li, Man, Chen, Han, Fuchsberger, Christian, Kwan, Phoenix, Ma, Clement, Linderman, Michael, Lu, Yingchang, Thomsen, Soren K, Rundle, Jana K, Beer, Nicola L, van de Bunt, Martijn, Chalisey, Anil, Kang, Hyun Min, Voight, Benjamin F, Abecasis, Goncalo R, Almgren, Peter, Baldassarre, Damiano, Balkau, Beverley, Benediktsson, Rafn, Blüher, Matthias, Boeing, Heiner, Bonnycastle, Lori L, Borringer, Erwin P, Burtt, Noël P, Carey, Jason, Charpentier, Guillaume, Chines, Peter S, Cornelis, Marilyn C, Couper, David J, Crenshaw, Andrew T, van Dam, Rob M, Doney, Alex SF, Dorkhan, Mozhgan, Edkins, Sarah, Eriksson, Johan G, Esko, Tonu, Eury, Elodie, Fadista, João, Flannick, Jason, Fontanillas, Pierre, Fox, Caroline, Franks, Paul W, Gertow, Karl, Gieger, Christian, Gigante, Bruna, Gottesman, Omri, Grant, George B, Grarup, Niels, Groves, Christopher J, Hassinen, Maija, Have, Christian T, Herder, Christian, Holmen, Oddgeir L, Hreidarsson, Astradur B, Humphries, Steve E, Hunter, David J, Jackson, Anne U, Jonsson, Anna, Jørgensen, Marit E, Jørgensen, Torben, Kao, Wen-Hong L, Kerrison, Nicola D, Kinnunen, Leena, Klopp, Norman, Kong, Augustine, Kovacs, Peter, Kraft, Peter, Kravic, Jasmina, Langford, Cordelia, Leander, Karin, Liang, Liming, Lichtner, Peter, Lindgren, Cecilia M, Lindholm, Eero, Linneberg, Allan, Liu, Ching-Ti, Lobbens, Stéphane, Luan, Jian’an, Lyssenko, Valeriya, Mӓnnistö, Satu, McLeod, Olga, Meyer, Julia, Mihailov, Evelin, Mirza, Ghazala, Mühleisen, Thomas W, Müller-Nurasyid, Martina, Navarro, Carmen, Nöthen, Markus M, Oskolkov, Nikolay N, Owen, Katharine R, Palli, Domenico, Pechlivanis, Sonali, Peltonen, Leena, Perry, John RB, Platou, Carl GP, Roden, Michael, Ruderfer, Douglas, Rybin, Denis, van der Schouw, Yvonne T, Sennblad, Bengt, Sigurđsson, Gunnar, Stančáková, Alena, Steinbach, Gerald, Storm, Petter, Strauch, Konstantin, Stringham, Heather M, Sun, Qi, Thorand, Barbara, Tikkanen, Emmi, Tonjes, Anke, Trakalo, Joseph, Tremoli, Elena, Tuomi, Tiinamaija, Wennauer, Roman, Wiltshire, Steven, Wood, Andrew R, Zeggini, Eleftheria, Dunham, Ian, Birney, Ewan, Pasquali, Lorenzo, Ferrer, Jorge, Loos, Ruth JF, Dupuis, Josée, Florez, Jose C, Boerwinkle, Eric, Pankow, James S, van Duijn, Cornelia, Sijbrands, Eric, Meigs, James B, Hu, Frank B, Thorsteinsdottir, Unnur, Stefansson, Kari, Lakka, Timo A, Rauramaa, Rainer, Stumvoll, Michael, Pedersen, Nancy L, Lind, Lars, Keinanen-Kiukaanniemi, Sirkka M, Korpi-Hyövӓlti, Eeva, Saaristo, Timo E, Saltevo, Juha, Kuusisto, Johanna, Laakso, Markku, Metspalu, Andres, Erbel, Raimund, Jöckel, Karl-Heinz, Moebus, Susanne, Ripatti, Samuli, Salomaa, Veikko, Ingelsson, Erik, Boehm, Bernhard O, Bergman, Richard N, Collins, Francis S, Mohlke, Karen L, Koistinen, Heikki, Tuomilehto, Jaakko, Hveem, Kristian, Njølstad, Inger, Deloukas, Panagiotis, Donnelly, Peter J, Frayling, Timothy M, Hattersley, Andrew T, de Faire, Ulf, Hamsten, Anders, Illig, Thomas, Peters, Annette, Cauchi, Stephane, Sladek, Rob, Froguel, Philippe, Hansen, Torben, Pedersen, Oluf, Morris, Andrew D, Palmer, Collin NA, Kathiresan, Sekar, Melander, Olle, Nilsson, Peter M, Groop, Leif C, Barroso, Inês, Langenberg, Claudia, Wareham, Nicholas J, O’Callaghan, Christopher A, Gloyn, Anna L, Altshuler, David, Boehnke, Michael, Teslovich, Tanya M, McCarthy, Mark I, Morris, Andrew P
Τόπος έκδοσης Nat Genet (2015)