Multiple myeloma/hypercalcemia

Por Oyajobi, Babatunde O
Publicado em 2007

Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling

Por Sung, Bokyung, Oyajobi, Babatunde O., Aggarwal, Bharat B.
Publicado em 2011

Functional Redundancy of Type II BMP Receptor and Type IIB Activin Receptor in BMP2-Induced Osteoblast Differentiation

Por LIU, HONGBIN, ZHANG, RONGRONG, CHEN, DI, OYAJOBI, BABATUNDE O., ZHAO, MING
Publicado em 2012

Bone marrow-targeted liposomal carriers

Por Sou, Keitaro, Goins, Beth, Oyajobi, Babatunde O., Travi, Bruno L., Phillips, William T.
Publicado em 2011

The Zinc Finger Transcription Factor Gli2 Mediates Bone Morphogenetic Protein 2 Expression in Osteoblasts in Response to Hedgehog Signaling

Por Zhao, Ming, Qiao, Mei, Harris, Stephen E., Chen, Di, Oyajobi, Babatunde O., Mundy, Gregory R.
Publicado em 2006

Smurf1 Inhibits Osteoblast Differentiation and Bone Formation in Vitro and in Vivo

Por Zhao, Ming, Qiao, Mei, Harris, Stephen E., Oyajobi, Babatunde O., Mundy, Gregory R., Chen, Di
Publicado em 2003

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

Por Zhang, Rongrong, Oyajobi, Babatunde O., Harris, Stephen E., Chen, Di, Tsao, Christopher, Deng, Hong-Wen, Zhao, Ming
Publicado em 2012

A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice

Por Sharma, Ramaswamy, Williams, Paul J., Gupta, Anjana, McCluskey, Brandon, Bhaskaran, Shylesh, Muñoz, Steve, Oyajobi, Babatunde O.
Publicado no Oncotarget (2015)

Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo

Por Edwards, Claire M., Lwin, Seint T., Fowler, Jessica A., Oyajobi, Babatunde O., Zhuang, Junling, Bates, Andreia L., Mundy, Gregory R.
Publicado em 2009

Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease

Por Oyajobi, Babatunde O., Garrett, I. Ross, Gupta, Anjana, Flores, Alda, Esparza, Javier, Muñoz, Steve, Zhao, Ming, Mundy, Gregory R.
Publicado no Br J Haematol (2007)

Combined treatment with a transforming growth factor beta inhibitor (1D11) and bortezomib improves bone architecture in a mouse model of myeloma-induced bone disease

Por Nyman, Jeffry S., Merkel, Alyssa R., Uppuganti, Sasidhar, Nayak, Bijaya, Rowland, Barbara, Makowski, Alexander J., Oyajobi, Babatunde O., Sterling, Julie A.
Publicado no Bone (2016)

Transcriptional Regulation of BMP2 Expression by the PTH-CREB Signaling Pathway in Osteoblasts

Por Zhang, Rongrong, Edwards, James R., Ko, Seon-Yle, Dong, Shanshan, Liu, Hongbin, Oyajobi, Babatunde O., Papasian, Christopher, Deng, Hong-Wen, Zhao, Ming
Publicado em 2011

Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice

Por Wang, Hua, Xiao, Lifeng, Tao, Jianguo, Srinivasan, Venkat, Boyce, Brendan F., Ebetino, Frank H., Oyajobi, Babatunde O., Boeckman, Robert K., Xing, Lianping
Publicado no Pharmaceutics (2018)

Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo

Por Edwards, Claire M., Edwards, James R., Lwin, Seint T., Esparza, Javier, Oyajobi, Babatunde O., McCluskey, Brandon, Munoz, Steven, Grubbs, Barry, Mundy, Gregory R.
Publicado em 2008

Inhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2

Por Zhao, Ming, Ko, Seon-Yle, Liu, Jin-Hua, Chen, Di, Zhang, Jianghong, Wang, Baolin, Harris, Stephen E., Oyajobi, Babatunde O., Mundy, Gregory R.
Publicado em 2009

TGF-β promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling...

Por Johnson, Rachelle W., Nguyen, Mai P., Padalecki, Susan S., Grubbs, Barry G., Merkel, Alyssa R., Oyajobi, Babatunde O., Matrisian, Lynn M., Mundy, Gregory R., Sterling, Julie A.
Publicado em 2010

Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging

Por Oyajobi, Babatunde O., Muñoz, Steve, Kakonen, Rami, Williams, Paul J., Gupta, Anjana, Wideman, Christi L., Story, Beryl, Grubbs, Barry, Armstrong, Allison, Dougall, William C., Garrett, I. Ross, Mundy, Gregory R.
Publicado no Mol Cancer Ther (2007)

CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

Por Dairaghi, Daniel J., Oyajobi, Babatunde O., Gupta, Anjana, McCluskey, Brandon, Miao, Shichang, Powers, Jay P., Seitz, Lisa C., Wang, Yu, Zeng, Yibin, Zhang, Penglie, Schall, Thomas J., Jaen, Juan C.
Publicado em 2012

Therapeutic anti-tumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma

Por Murillo, Oihana, Arina, Ainhoa, Hervas-Stubbs, Sandra, Gupta, Anjana, McCluskey, Brandon, Dubrot, Juan, Palazón, Asís, Azpilikueta, Arantza, Ochoa, Maria C., Alfaro, Carlos, Solano, Sarai, Pérez-Gracia, José L., Oyajobi, Babatunde O., Melero, Ignacio
Publicado em 2008

Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

Por De Veirman, Kim, Van Ginderachter, Jo A., Lub, Susanne, De Beule, Nathan, Thielemans, Kris, Bautmans, Ivan, Oyajobi, Babatunde O., De Bruyne, Elke, Menu, Eline, Lemaire, Miguel, Van Riet, Ivan, Vanderkerken, Karin, Van Valckenborgh, Els
Publicado no Oncotarget (2015)