How Do Bisphosphonates Inhibit Bone Metastasis In Vivo?

Por Fournier, Pierrick G, Stresing, Verena, Ebetino, Frank H, Clézardin, Philippe
Publicado em 2010

Bisphosphonates Improve Trabecular Bone Mass and Normalize Cortical Thickness in Ovariectomized, Osteoblast Connexin43 Deficient Mice

Por Watkins, Marcus P., Norris, Jin Yi, Grimston, Susan K., Zhang, Xiaowen, Phipps, Roger J., Ebetino, Frank H., Civitelli, Roberto
Publicado em 2012

Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice

Por Sugiyama, Toshihiro, Meakin, Lee B., Galea, Gabriel L., Jackson, Brendan F., Lanyon, Lance E., Ebetino, Frank H., Russell, R. Graham G., Price, Joanna S.
Publicado em 2011

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

Por Kavanagh, Kathryn L., Guo, Kunde, Dunford, James E., Wu, Xiaoqiu, Knapp, Stefan, Ebetino, Frank H., Rogers, Michael J., Russell, R. Graham G., Oppermann, Udo
Publicado em 2006

Synthesis and characterization of novel fluorescent nitrogen-containing bisphosphonate imaging probes for bone active drugs

Por Sun, Shuting, Błażewska, Katarzyna M., Kashemirov, Boris A., Roelofs, Anke J., Coxon, Fraser P., Rogers, Michael J., Ebetino, Frank H., McKenna, Michael J., McKenna, Charles E.
Publicado em 2011

Phosphonocarboxylates Inhibit the Second Geranylgeranyl Addition by Rab Geranylgeranyl Transferase

Por Baron, Rudi A., Tavaré, Richard, Figueiredo, Ana C., Błażewska, Katarzyna M., Kashemirov, Boris A., McKenna, Charles E., Ebetino, Frank H., Taylor, Adam, Rogers, Michael J., Coxon, Fraser P., Seabra, Miguel C.
Publicado em 2009

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using en...

Por Tsoumpra, Maria K., Muniz, Joao R., Barnett, Bobby L., Kwaasi, Aaron A., Pilka, Ewa S., Kavanagh, Kathryn L., Evdokimov, Artem, Walter, Richard L., Von Delft, Frank, Ebetino, Frank H., Oppermann, Udo, Russell, R. Graham G., Dunford, James E.
Publicado no Bone (2015)

Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine

Por Sun, Shuting, Błażewska, Katarzyna M., Kadina, Anastasia P., Kashemirov, Boris A., Duan, Xuchen, Triffitt, James T., Dunford, James E., Russell, R. Graham G., Ebetino, Frank H., Roelofs, Anke J., Coxon, Fraser P., Lundy, Mark W., McKenna, Charles E.
Publicado no Bioconjug Chem (2015)

Fluorescent Risedronate Analogues Reveal Bisphosphonate Uptake by Bone Marrow Monocytes and Localization Around Osteocytes In Vivo

Por Roelofs, Anke J, Coxon, Fraser P, Ebetino, Frank H, Lundy, Mark W, Henneman, Zachary J, Nancollas, George H, Sun, Shuting, Blazewska, Katarzyna M, Bala, Joy Lynn F, Kashemirov, Boris A, Khalid, Aysha B, McKenna, Charles E, Rogers, Michael J
Publicado em 2010