Assessment of radiation damage behaviour in a large collection of empirically optimized datasets highlights the importance of unmeasured complicating effects

Por Krojer, Tobias, von Delft, Frank
Publicado em 2011

Molecular replacement

Por Murshudov, Garib, von Delft, Frank, Ballard, Charles
Publicado em 2008

Crystal structures of human soluble guanylate cyclase catalytic domains: promiscuity of the dimer interface and a potential allosteric site

Por Gileadi, Opher, Allerston, Charles, von Delft, Frank
Publicado em 2013

Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens

Por Chaikuad, Apirat, Knapp, Stefan, von Delft, Frank
Publicado no Acta Crystallogr D Biol Crystallogr (2015)

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73

Por Canning, Peter, von Delft, Frank, Bullock, Alex N.
Publicado em 2012

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

Por Allerston, Charles K., von Delft, Frank, Gileadi, Opher
Publicado em 2013

Proper modelling of ligand binding requires an ensemble of bound and unbound states

Por Pearce, Nicholas M., Krojer, Tobias, von Delft, Frank
Publicado no Acta Crystallogr D Struct Biol (2017)

Squeezing the most from every crystal: the fine details of data collection

Por Krojer, Tobias, Pike, Ashley C. W., von Delft, Frank
Publicado em 2013

Lessons from ten years of crystallization experiments at the SGC

Por Ng, Jia Tsing, Dekker, Carien, Reardon, Paul, von Delft, Frank
Publicado no Acta Crystallogr D Struct Biol (2016)

Using textons to rank crystallization droplets by the likely presence of crystals

Por Ng, Jia Tsing, Dekker, Carien, Kroemer, Markus, Osborne, Michael, von Delft, Frank
Publicado em 2014

Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class

Por Salah, Eidarus, Ugochukwu, Emilie, Barr, Alastair J., von Delft, Frank, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2011

Conformational plasticity of glycogenin and its maltosaccharide substrate during glycogen biogenesis

Por Chaikuad, Apirat, Froese, D. Sean, Berridge, Georgina, von Delft, Frank, Oppermann, Udo, Yue, Wyatt W.
Publicado em 2011

An overview of heavy-atom derivatization of protein crystals

Por Pike, Ashley C. W., Garman, Elspeth F., Krojer, Tobias, von Delft, Frank, Carpenter, Elisabeth P.
Publicado no Acta Crystallogr D Struct Biol (2016)

The Crystal Structure of Shikimate Dehydrogenase (AroE) Reveals a Unique NADPH Binding Mode

Por Ye, Sheng, von Delft, Frank, Brooun, Alexei, Knuth, Mark W., Swanson, Ronald V., McRee, Duncan E.
Publicado em 2003

A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis

Por Kerr, Georgina, Sheldon, Helen, Chaikuad, Apirat, Alfano, Ivan, von Delft, Frank, Bullock, Alex N., Harris, Adrian L.
Publicado no Angiogenesis (2015)

Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites

Por Pearce, Nicholas M., Bradley, Anthony R., Krojer, Tobias, Marsden, Brian D., Deane, Charlotte M., von Delft, Frank
Publicado no Struct Dyn (2017)

Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits

Por Shafqat, Naeem, Muniz, Joao R. C., Pilka, Ewa S., Papagrigoriou, Evangelos, vonDelft, Frank, Oppermann, Udo, Yue, Wyatt W.
Publicado em 2013

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

Por Rellos, Peter, Pike, Ashley C. W., Niesen, Frank H., Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan
Publicado em 2010

Molecular Architecture of the Ankyrin SOCS Box Family of Cul5-Dependent E3 Ubiquitin Ligases

Por Muniz, João R.C., Guo, Kunde, Kershaw, Nadia J., Ayinampudi, Vikram, von Delft, Frank, Babon, Jeffrey J., Bullock, Alex N.
Publicado em 2013

Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16

Por Dixon-Clarke, Sarah E., Shehata, Saifeldin N., Krojer, Tobias, Sharpe, Timothy D., vonDelft, Frank, Sakamoto, Kei, Bullock, Alex N.
Publicado no Biochem J (2017)