Fluorescent Risedronate Analogues Reveal Bisphosphonate Uptake by Bone Marrow Monocytes and Localization Around Osteocytes In Vivo

Bisphosphonates are effective antiresorptive agents owing to their bone-targeting property and ability to inhibit osteoclasts. It remains unclear, however, whether any non-osteoclast cells are directly affected by these drugs in vivo. Two fluorescent risedronate analogues, carboxyfluorescein-labeled...

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Detalhes bibliográficos
Main Authors: Roelofs, Anke J, Coxon, Fraser P, Ebetino, Frank H, Lundy, Mark W, Henneman, Zachary J, Nancollas, George H, Sun, Shuting, Blazewska, Katarzyna M, Bala, Joy Lynn F, Kashemirov, Boris A, Khalid, Aysha B, McKenna, Charles E, Rogers, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153397/
https://ncbi.nlm.nih.gov/pubmed/20422624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/jbmr.091009
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