Non-ototoxic local delivery of bisphosphonate to the mammalian cochlea

HYPOTHESIS: Local delivery of bisphosphonates results in superior localization of these compounds for the treatment of cochlear otosclerosis, without ototoxicity. BACKGROUND: Otosclerosis is a common disorder of abnormal bone remodeling within the human otic capsule. It is a frequent cause of conduc...

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Bibliographic Details
Published in:Otol Neurotol
Main Authors: Kang, Woo Seok, Sun, Shuting, Nguyen, Kim, Kashemirov, Boris, McKenna, Charles E., Hacking, S. Adam, Quesnel, Alicia M., Sewell, William F., McKenna, Michael J., Jung, David H.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469560/
https://ncbi.nlm.nih.gov/pubmed/25996080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MAO.0000000000000786
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