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Bisphosphonate binding affinity as assessed by inhibition of carbonated apatite dissolution in vitro

Bisphosphonates (BPs), which display a high affinity for calcium phosphate surfaces, are able to selectively target bone mineral, where they are potent inhibitors of osteoclast-mediated bone resorption. The dissolution of synthetic hydroxyapatite (HAP) has been used previously as a model for BP effe...

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Detalhes bibliográficos
Main Authors: Henneman, Zachary J., Nancollas, George H., Ebetino, F. Hal, Russell, R. Graham G., Phipps, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743543/
https://ncbi.nlm.nih.gov/pubmed/17907244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.31599
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