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Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSC) are contributing to an immunosuppressive environment by their ability to inhibit T cell activity and thereby promoting cancer progression. An important feature of the incurable plasma cell malignancy Multiple Myeloma (MM) is immune dysfunction. MDSC were previ...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: De Veirman, Kim, Van Ginderachter, Jo A., Lub, Susanne, De Beule, Nathan, Thielemans, Kris, Bautmans, Ivan, Oyajobi, Babatunde O., De Bruyne, Elke, Menu, Eline, Lemaire, Miguel, Van Riet, Ivan, Vanderkerken, Karin, Van Valckenborgh, Els
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496373/
https://ncbi.nlm.nih.gov/pubmed/25871384
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