Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSC) are contributing to an immunosuppressive environment by their ability to inhibit T cell activity and thereby promoting cancer progression. An important feature of the incurable plasma cell malignancy Multiple Myeloma (MM) is immune dysfunction. MDSC were previ...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: De Veirman, Kim, Van Ginderachter, Jo A., Lub, Susanne, De Beule, Nathan, Thielemans, Kris, Bautmans, Ivan, Oyajobi, Babatunde O., De Bruyne, Elke, Menu, Eline, Lemaire, Miguel, Van Riet, Ivan, Vanderkerken, Karin, Van Valckenborgh, Els
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496373/
https://ncbi.nlm.nih.gov/pubmed/25871384
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