Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSC) are contributing to an immunosuppressive environment by their ability to inhibit T cell activity and thereby promoting cancer progression. An important feature of the incurable plasma cell malignancy Multiple Myeloma (MM) is immune dysfunction. MDSC were previ...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: De Veirman, Kim, Van Ginderachter, Jo A., Lub, Susanne, De Beule, Nathan, Thielemans, Kris, Bautmans, Ivan, Oyajobi, Babatunde O., De Bruyne, Elke, Menu, Eline, Lemaire, Miguel, Van Riet, Ivan, Vanderkerken, Karin, Van Valckenborgh, Els
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496373/
https://ncbi.nlm.nih.gov/pubmed/25871384
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