The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells

Exosomes, extracellular nanovesicles secreted by various cell types, modulate the bone marrow (BM) microenvironment by regulating angiogenesis, cytokine release, immune response, inflammation, and metastasis. Interactions between bone marrow stromal cells (BMSCs) and multiple myeloma (MM) cells play...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Jinheng, De Veirman, Kim, De Beule, Nathan, Maes, Ken, De Bruyne, Elke, Van Valckenborgh, Els, Vanderkerken, Karin, Menu, Eline
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791281/
https://ncbi.nlm.nih.gov/pubmed/26556857
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