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Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models

Multiple myeloma (MM) is the second most common hematological malignancy and is characterized by the clonal expansion of plasma cells in the bone marrow. Recently, hypoxia has received increased interest in the context of MM, in both basic and translational research. In this review, we describe the...

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Hlavní autoři: Hu, Jinsong, Van Valckenborgh, Els, Menu, Eline, De Bruyne, Elke, Vanderkerken, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484859/
https://ncbi.nlm.nih.gov/pubmed/23115205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008961
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