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Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models

Multiple myeloma (MM) is the second most common hematological malignancy and is characterized by the clonal expansion of plasma cells in the bone marrow. Recently, hypoxia has received increased interest in the context of MM, in both basic and translational research. In this review, we describe the...

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Detalhes bibliográficos
Main Authors: Hu, Jinsong, Van Valckenborgh, Els, Menu, Eline, De Bruyne, Elke, Vanderkerken, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484859/
https://ncbi.nlm.nih.gov/pubmed/23115205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008961
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