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The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential

Multiple myeloma (MM) is a highly heterogeneous plasma cell malignancy. The MM cells reside in the bone marrow (BM), where reciprocal interactions with the BM niche foster MM cell survival, proliferation, and drug resistance. As in most cancers, the insulin-like growth factor (IGF) system has been d...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Bieghs, Liesbeth, Johnsen, Hans E., Maes, Ken, Menu, Eline, Van Valckenborgh, Els, Overgaard, Michael T., Nyegaard, Mette, Conover, Cheryl A., Vanderkerken, Karin, De Bruyne, Elke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217049/
https://ncbi.nlm.nih.gov/pubmed/27129151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8982
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