Determining immune components necessary for progression of pigment dispersing disease to glaucoma in DBA/2J mice

od Nair, K Saidas, Barbay, Jessica, Smith, Richard S, Masli, Sharmila, John, Simon WM
Wydane 2014

Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation

od Koli, Swanand, Labelle-Dumais, Cassandre, Zhao, Yin, Paylakhi, Seyyedhassan, Nair, K. Saidas
Wydane w PLoS Genet (2021)

Gpnmb(R150X )allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma

od Anderson, Michael G, Nair, K Saidas, Amonoo, Leslie A, Mehalow, Adrienne, Trantow, Colleen M, Masli, Sharmila, John, Simon WM
Wydane 2008

Interaction of retinal guanylate cyclase with the α subunit of transducin: potential role in transducin localization

od ROSENZWEIG, Derek H., NAIR, K. SAIDAS, LEVAY, Konstantin, PESHENKO, Igor V., CRABB, John W., DIZHOOR, Alexander M., SLEPAK, Vladlen Z.
Wydane 2009

YBR/EiJ mice: a new model of glaucoma caused by genes on chromosomes 4 and 17

od Nair, K. Saidas, Cosma, Mihai, Raghupathy, Narayanan, Sellarole, Michael A., Tolman, Nicholas G., de Vries, Wilhelmine, Smith, Richard S., John, Simon W. M.
Wydane w Dis Model Mech (2016)

A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure

od Choquet, Hélène, Thai, Khanh K., Yin, Jie, Hoffmann, Thomas J., Kvale, Mark N., Banda, Yambazi, Schaefer, Catherine, Risch, Neil, Nair, K. Saidas, Melles, Ronald, Jorgenson, Eric
Wydane w Nat Commun (2017)

Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity

od Hanson, Susan M., Cleghorn, Whitney M., Francis, Derek J., Vishnivetskiy, Sergey A., Raman, Dayanidhi, Song, Xiufeng, Nair, K. Saidas, Slepak, Vladlen Z., Klug, Candice S., Gurevich, Vsevolod V.
Wydane 2007

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

od Choquet, Hélène, Melles, Ronald B., Anand, Deepti, Yin, Jie, Cuellar-Partida, Gabriel, Wang, Wei, Hoffmann, Thomas J., Nair, K. Saidas, Hysi, Pirro G., Lachke, Salil A., Jorgenson, Eric
Wydane w Nat Commun (2021)

Using Genetic Mouse Models to Gain Insight into Glaucoma: Past Results and Future Possibilities

od Fernandes, Kimberly A., Harder, Jeffrey M., Williams, Pete A., Rausch, Rebecca L., Kiernan, Amy E., Nair, K. Saidas, Anderson, Michael G., John, Simon W., Howell, Gareth R., Libby, Richard T.
Wydane w Exp Eye Res (2015)

Subunit Dissociation and Diffusion Determine the Subcellular Localization of Rod and Cone Transducins

od Rosenzweig, Derek H., Nair, K. Saidas, Wei, Junhua, Wang, Qiang, Garwin, Greg, Saari, John C., Chen, Ching-Kang, Smrcka, Alan V., Swaroop, Anand, Lem, Janis, Hurley, James B., Slepak, Vladlen Z.
Wydane 2007

Light-Dependent Redistribution of Arrestin in Vertebrate Rods Is an Energy-Independent Process Governed by Protein-Protein Interactions

od Nair, K. Saidas, Hanson, Susan M., Mendez, Ana, Gurevich, Eugenia V., Kennedy, Matthew J., Shestopalov, Valery I., Vishnivetskiy, Sergey A., Chen, Jeannie, Hurley, James B., Gurevich, Vsevolod V., Slepak, Vladlen Z.
Wydane 2005

Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error

od Paylakhi, Seyyedhassan, Labelle-Dumais, Cassandre, Tolman, Nicholas G, Sellarole, Michael A., Seymens, Yusef, Saunders, Joseph, Lakosha, Hesham, deVries, Wilhelmine N., Orr, Andrew C., Topilko, Piotr, John, Simon WM., Nair, K. Saidas
Wydane w PLoS Genet (2018)

Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure

od Labelle-Dumais, Cassandre, Pyatla, Goutham, Paylakhi, Seyyedhassan, Tolman, Nicholas G., Hameed, Syed, Seymens, Yusef, Dang, Eric, Mandal, Anil K., Senthil, Sirisha, Khanna, Rohit C., Kabra, Meha, Kaur, Inderjeet, John, Simon W. M., Chakrabarti, Subhabrata, Nair, K. Saidas
Wydane w Dis Model Mech (2020)

Genetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice

od Tolman, Nicholas G., Balasubramanian, Revathi, Macalinao, Danilo G., Kearney, Alison L., MacNicoll, Katharine H., Montgomery, Christa L., de Vries, Wilhelmine N., Jackson, Ian J., Cross, Sally H., Kizhatil, Krishnakumar, Nair, K. Saidas, John, Simon W. M.
Wydane w Dis Model Mech (2021)

A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness

od Choquet, Hélène, Melles, Ronald B., Yin, Jie, Hoffmann, Thomas J., Thai, Khanh K., Kvale, Mark N., Banda, Yambazi, Hardcastle, Alison J., Tuft, Stephen J., Glymour, M. Maria, Schaefer, Catherine, Risch, Neil, Nair, K. Saidas, Hysi, Pirro G., Jorgenson, Eric
Wydane w Commun Biol (2020)

Alteration of the serine protease PRSS56 causes angle-closure glaucoma in mice and posterior microphthalamia in humans and mice

od Nair, K Saidas, Hmani-Aifa, Mounira, Ali, Zain, Kearney, Alison L, Salem, Salma Ben, Macalinao, Danilo G, Cosma, Ioan M, Bouassida, Walid, Hakim, Bochra, Benzina, Zeineb, Soto, Ileana, Söderkvist, Peter, Howell, Gareth R, Smith, Richard S, Ayadi, Hammadi, John, Simon W M
Wydane w Nat Genet (2011)

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

od Choquet, Hélène, Paylakhi, Seyyedhassan, Kneeland, Stephen C., Thai, Khanh K., Hoffmann, Thomas J., Yin, Jie, Kvale, Mark N., Banda, Yambazi, Tolman, Nicholas G., Williams, Pete A., Schaefer, Catherine, Melles, Ronald B., Risch, Neil, John, Simon W. M., Nair, K. Saidas, Jorgenson, Eric
Wydane w Nat Commun (2018)

Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma

od Lachke, Salil A., Alkuraya, Fowzan S., Kneeland, Stephen C., Ohn, Takbum, Aboukhalil, Anton, Howell, Gareth R., Saadi, Irfan, Cavallesco, Resy, Yue, Yingzi, Tsai, Anne C-H., Nair, K. Saidas, Cosma, Mihai I., Smith, Richard S., Hodges, Emily, AlFadhli, Suad M., Al-Hajeri, Amal, Shamseldin, Hanan E., Behbehani, AbdulMutalib, Hannon, Gregory J., Bulyk, Martha L., Drack, Arlene V., Anderson, Paul J., John, Simon W. M., Maas, Richard L.
Wydane 2011

ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

od Nongpiur, Monisha E., Khor, Chiea Chuen, Jia, Hongyan, Cornes, Belinda K., Chen, Li-Jia, Qiao, Chunyan, Nair, K. Saidas, Cheng, Ching-Yu, Xu, Liang, George, Ronnie, Tan, Do, Abu-Amero, Khaled, Perera, Shamira A., Ozaki, Mineo, Mizoguchi, Takanori, Kurimoto, Yasuo, Low, Sancy, Tajudin, Liza-Sharmini A., Ho, Ching-Lin, Tham, Clement C. Y., Soto, Ileana, Chew, Paul T. K., Wong, Hon-Tym, Shantha, Balekudaru, Kuroda, Masako, Osman, Essam A., Tang, Guangxian, Fan, Sujie, Meng, Hailin, Wang, Hua, Feng, Bo, Yong, Victor H. K., Ting, Serena M. L., Li, Yang, Wang, Ya-Xing, Li, Zheng, Lavanya, Raghavan, Wu, Ren-Yi, Zheng, Ying-Feng, Su, Daniel H., Loon, Seng-Chee, Allingham, R. Rand, Hauser, Michael A., Soumittra, Nagaswamy, Ramprasad, Vedam L., Waseem, Naushin, Yaakub, Azhany, Chia, Kee-Seng, Kumaramanickavel, Govindasamy, Wong, Tina T., How, Alicia C., Chau, Tran Nguyen Bich, Simmons, Cameron P., Bei, Jin-Xin, Zeng, Yi-Xin, Bhattacharya, Shomi S., Zhang, Mingzhi, Tan, Donald T., Teo, Yik-Ying, Al-Obeidan, Saleh A., Hon, Do Nhu, Tai, E-Shyong, Saw, Seang-Mei, Foster, Paul J., Vijaya, Lingam, Jonas, Jost B., Wong, Tien-Yin, John, Simon W. M., Pang, Chi-Pui, Vithana, Eranga N., Wang, Ningli, Aung, Tin
Wydane 2014

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

od Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.
Wydane w Nat Commun (2021)