A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure

Elevated intraocular pressure (IOP) is a major risk factor for glaucoma, a leading cause of blindness. IOP heritability has been estimated to up to 67%, and to date only 11 IOP loci have been reported, accounting for 1.5% of IOP variability. Here, we conduct a genome-wide association study of IOP in...

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Pubblicato in:Nat Commun
Autori principali: Choquet, Hélène, Thai, Khanh K., Yin, Jie, Hoffmann, Thomas J., Kvale, Mark N., Banda, Yambazi, Schaefer, Catherine, Risch, Neil, Nair, K. Saidas, Melles, Ronald, Jorgenson, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727399/
https://ncbi.nlm.nih.gov/pubmed/29235454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01913-6
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