Subunit Dissociation and Diffusion Determine the Subcellular Localization of Rod and Cone Transducins

Activation of rod photoreceptors by light induces a massive redistribution of the heterotrimeric G-protein transducin. In darkness, transducin is sequestered within the membrane-enriched outer segments of the rod cell. In light, it disperses throughout the entire neuron. We show here that redistribu...

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Main Authors: Rosenzweig, Derek H., Nair, K. Saidas, Wei, Junhua, Wang, Qiang, Garwin, Greg, Saari, John C., Chen, Ching-Kang, Smrcka, Alan V., Swaroop, Anand, Lem, Janis, Hurley, James B., Slepak, Vladlen Z.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2007
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655354/
https://ncbi.nlm.nih.gov/pubmed/17507570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1421-07.2007
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