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A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin

PURPOSE: Rhodopsin mutations account for approximately 25% of human autosomal dominant retinal degenerations. However, the molecular mechanisms by which rhodopsin mutations cause photoreceptor cell death are unclear. Mutations in genes involved in the termination of rhodopsin signaling activity have...

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Detalhes bibliográficos
Main Authors: Brill, Elliott, Malanson, Katherine M., Radu, Roxana A., Boukharov, Natalia V., Wang, Zhongyan, Chung, Hae-Yun, Lloyd, Marcia B., Bok, Dean, Travis, Gabriel H., Obin, Martin, Lem, Janis
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248236/
https://ncbi.nlm.nih.gov/pubmed/18055791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-1402
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