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A Novel Form of Transducin-Dependent Retinal Degeneration: Accelerated Retinal Degeneration in the Absence of Rod Transducin

PURPOSE: Rhodopsin mutations account for approximately 25% of human autosomal dominant retinal degenerations. However, the molecular mechanisms by which rhodopsin mutations cause photoreceptor cell death are unclear. Mutations in genes involved in the termination of rhodopsin signaling activity have...

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Détails bibliographiques
Auteurs principaux: Brill, Elliott, Malanson, Katherine M., Radu, Roxana A., Boukharov, Natalia V., Wang, Zhongyan, Chung, Hae-Yun, Lloyd, Marcia B., Bok, Dean, Travis, Gabriel H., Obin, Martin, Lem, Janis
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248236/
https://ncbi.nlm.nih.gov/pubmed/18055791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-1402
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