Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure

Glaucoma is a leading cause of blindness, affecting up to 70 million people worldwide. High intraocular pressure (IOP) is a major risk factor for glaucoma. It is well established that inefficient aqueous humor (AqH) outflow resulting from structural or functional alterations in ocular drainage tissu...

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Dades bibliogràfiques
Publicat a:Dis Model Mech
Autors principals: Labelle-Dumais, Cassandre, Pyatla, Goutham, Paylakhi, Seyyedhassan, Tolman, Nicholas G., Hameed, Syed, Seymens, Yusef, Dang, Eric, Mandal, Anil K., Senthil, Sirisha, Khanna, Rohit C., Kabra, Meha, Kaur, Inderjeet, John, Simon W. M., Chakrabarti, Subhabrata, Nair, K. Saidas
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272341/
https://ncbi.nlm.nih.gov/pubmed/32152063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.042853
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