Support for the involvement of complement factor I in age-related macular degeneration

le Ennis, Sarah, Gibson, Jane, Cree, Angela J, Collins, Andrew, Lotery, Andrew J
Foilsithe 2010

Complement factor I and age-related macular degeneration

le Alexander, Philip, Gibson, Jane, Cree, Angela J., Ennis, Sarah, Lotery, Andrew J.
Foilsithe 2014

A novel, wearable, electronic visual aid to assist those with reduced peripheral vision

le Brown, Ffion E., Sutton, Janice, Yuen, Ho M., Green, Dylan, Van Dorn, Spencer, Braun, Terry, Cree, Angela J., Russell, Stephen R., Lotery, Andrew J.
Foilsithe in PLoS One (2019)

Rare Genetic Variants in Complement Factor I Lead to Low FI Plasma Levels Resulting in Increased Risk of Age-Related Macular Degeneration

le Hallam, Thomas M., Marchbank, Kevin J., Harris, Claire L., Osmond, Clive, Shuttleworth, Victoria G., Griffiths, Helen, Cree, Angela J., Kavanagh, David, Lotery, Andrew J.
Foilsithe in Invest Ophthalmol Vis Sci (2020)

Comprehensive sequencing of the myocilin gene in a selected cohort of severe primary open-angle glaucoma patients

le O’Gorman, Luke, Cree, Angela J., Ward, Daniel, Griffiths, Helen L., Sood, Roshan, Denniston, Alastair K., Self, Jay E., Ennis, Sarah, Lotery, Andrew J., Gibson, Jane
Foilsithe in Sci Rep (2019)

A convenient protocol for establishing a human cell culture model of the outer retina.

le Lynn, Savannah A., Keeling, Eloise, Dewing, Jennifer M., Johnston, David A., Page, Anton, Cree, Angela J., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Foilsithe in F1000Res (2018)

Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE

le Lynn, Savannah A., Ward, Gareth, Keeling, Eloise, Scott, Jenny A., Cree, Angela J., Johnston, David A., Page, Anton, Cuan-Urquizo, Enrique, Bhaskar, Atul, Grossel, Martin C., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Foilsithe in Tissue Cell (2017)

A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping

le O’Gorman, Luke, Norman, Chelsea S., Michaels, Luke, Newall, Tutte, Crosby, Andrew H., Mattocks, Christopher, Cree, Angela J., Lotery, Andrew J., Baple, Emma L., Ratnayaka, J. Arjuna, Baralle, Diana, Lee, Helena, Osborne, Daniel, Shawkat, Fatima, Gibson, Jane, Ennis, Sarah, Self, Jay E.
Foilsithe in Sci Rep (2019)

Oligomeric Aβ(1-42) Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

le Lynn, Savannah A., Johnston, David A., Scott, Jenny A., Munday, Rosie, Desai, Roshni S., Keeling, Eloise, Weaterton, Ruaridh, Simpson, Alexander, Davis, Dillon, Freeman, Thomas, Chatelet, David S., Page, Anton, Cree, Angela J., Lee, Helena, Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Foilsithe in Cells (2021)

The Complement Component 5 gene and Age-related Macular Degeneration

le Baas, Dominique C., Ho, Lintje, Ennis, Sarah, Merriam, Joanna E., Tanck, Michael W.T., Uitterlinden, André G., de Jong, Paulus T.V.M., Cree, Angela J., Griffiths, Helen L., Rivadeneira, Fernando, Hofman, Albert, van Duijn, Cornelia, Smith, R. Theodore, Barile, Gaetano R., Gorgels, Theo G.M.F., Vingerling, Johannes R., Klaver, Caroline C.W., Lotery, Andrew J., Allikmets, Rando, Bergen, Arthur A.B.
Foilsithe 2009

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

le Bonnemaijer, Pieter W. M., Leeuwen, Elisabeth M. van, Iglesias, Adriana I., Gharahkhani, Puya, Vitart, Veronique, Khawaja, Anthony P., Simcoe, Mark, Höhn, René, Cree, Angela J., Igo, Rob P., Gerhold-Ay, Aslihan, Nickels, Stefan, Wilson, James F., Hayward, Caroline, Boutin, Thibaud S., Polašek, Ozren, Aung, Tin, Khor, Chiea Chuen, Amin, Najaf, Lotery, Andrew J., Wiggs, Janey L., Cheng, Ching-Yu, Hysi, Pirro G., Hammond, Christopher J., Thiadens, Alberta A. H. J., MacGregor, Stuart, Klaver, Caroline C. W., Duijn, Cornelia M. van
Foilsithe in Commun Biol (2019)

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB–FKBPL–NOTCH4 region of chromosome 6p21.3

le Cipriani, Valentina, Leung, Hin-Tak, Plagnol, Vincent, Bunce, Catey, Khan, Jane C., Shahid, Humma, Moore, Anthony T., Harding, Simon P., Bishop, Paul N., Hayward, Caroline, Campbell, Susan, Armbrecht, Ana Maria, Dhillon, Baljean, Deary, Ian J., Campbell, Harry, Dunlop, Malcolm, Dominiczak, Anna F., Mann, Samantha S., Jenkins, Sharon A., Webster, Andrew R., Bird, Alan C., Lathrop, Mark, Zelenika, Diana, Souied, Eric H., Sahel, José-Alain, Léveillard, Thierry, Cree, Angela J., Gibson, Jane, Ennis, Sarah, Lotery, Andrew J., Wright, Alan F., Clayton, David G., Yates, John R.W.
Foilsithe 2012

Association of Genetic Variants With Response to Anti–Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration

le Lorés-Motta, Laura, Riaz, Moeen, Grunin, Michelle, Corominas, Jordi, van Asten, Freekje, Pauper, Marc, Leenders, Mathieu, Richardson, Andrea J., Muether, Philipp, Cree, Angela J., Griffiths, Helen L., Pham, Connie, Belanger, Marie-Claude, Meester-Smoor, Magda A., Ali, Manir, Heid, Iris M., Fritsche, Lars G., Chakravarthy, Usha, Gale, Richard, McKibbin, Martin, Inglehearn, Chris F., Schlingemann, Reinier O., Omar, Amer, Chen, John, Koenekoop, Robert K., Fauser, Sascha, Guymer, Robyn H., Hoyng, Carel B., de Jong, Eiko K., Lotery, Andrew J., Mitchell, Paul, den Hollander, Anneke I., Baird, Paul N., Chowers, Itay
Foilsithe in JAMA Ophthalmol (2018)

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

le Thorleifsson, Gudmar, Walters, G Bragi, Hewitt, Alex W, Masson, Gisli, Helgason, Agnar, DeWan, Andrew, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Gudjonsson, Sigurjon A, Magnusson, Kristinn P, Stefansson, Hreinn, Lam, Dennis S C, Tam, Pancy O S, Gudmundsdottir, Gudrun J, Southgate, Laura, Burdon, Kathryn P, Gottfredsdottir, Maria Soffia, Aldred, Micheala A, Mitchell, Paul, St Clair, David, Collier, David A, Tang, Nelson, Sveinsson, Orn, Macgregor, Stuart, Martin, Nicholas G, Cree, Angela J, Gibson, Jane, MacLeod, Alex, Jacob, Aby, Ennis, Sarah, Young, Terri L, Chan, Juliana C N, Karwatowski, Wojciech S S, Hammond, Christopher J, Thordarson, Kristjan, Zhang, Mingzhi, Wadelius, Claes, Lotery, Andrew J, Trembath, Richard C, Pang, Chi Pui, Hoh, Josephine, Craig, Jamie E, Kong, Augustine, Mackey, David A, Jonasson, Fridbert, Thorsteinsdottir, Unnur, Stefansson, Kari
Foilsithe 2010

Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype

le Sofat, Reecha, Casas, Juan P, Webster, Andrew R, Bird, Alan C, Mann, Samantha S, Yates, John RW, Moore, Anthony T, Sepp, Tiina, Cipriani, Valentina, Bunce, Catey, Khan, Jane C, Shahid, Humma, Swaroop, Anand, Abecasis, Gonçalo, Branham, Kari E H, Zareparsi, Sepideh, Bergen, Arthur A, Klaver, Caroline CW, Baas, Dominique C, Zhang, Kang, Chen, Yuhong, Gibbs, Daniel, Weber, Bernhard H F, Keilhauer, Claudia N, Fritsche, Lars G, Lotery, Andrew, Cree, Angela J, Griffiths, Helen L, Bhattacharya, Shomi S, Chen, Li L, Jenkins, Sharon A, Peto, Tunde, Lathrop, Mark, Leveillard, Thierry, Gorin, Michael B, Weeks, Daniel E, Ortube, Maria Carolina, Ferrell, Robert E, Jakobsdottir, Johanna, Conley, Yvette P, Rahu, Mati, Seland, Johan H, Soubrane, Gisele, Topouzis, Fotis, Vioque, Jesus, Tomazzoli, Laura, Young, Ian, Whittaker, John, Chakravarthy, Usha, de Jong, Paulus T V M, Smeeth, Liam, Fletcher, Astrid, Hingorani, Aroon D
Foilsithe 2012

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

le Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P., Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W., Segrè, Ayellet V., Rouhana, John M., Hamel, Andrew R., Igo, Robert P., Choquet, Helene, Qassim, Ayub, Josyula, Navya S., Cooke Bailey, Jessica N., Bonnemaijer, Pieter W. M., Iglesias, Adriana, Siggs, Owen M., Young, Terri L., Vitart, Veronique, Thiadens, Alberta A. H. J., Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B., Nair, K. Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J., Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K., Martin, Nicholas G., Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E., Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J., Khaw, Peng T., Morgan, James E., Strouthidis, Nicholas G., Kraft, Peter, Kang, Jae H., Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J., Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L., Hammond, Chris, Pasquale, Louis R., Klaver, Caroline C. W., Hauser, Michael, Khor, Chiea Chuen, Mackey, David A., Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E., MacGregor, Stuart, Wiggs, Janey L.
Foilsithe in Nat Commun (2021)

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

le Springelkamp, Henriët., Höhn, René, Mishra, Aniket, Hysi, Pirro G., Khor, Chiea-Chuen, Loomis, Stephanie J., Bailey, Jessica N. Cooke, Gibson, Jane, Thorleifsson, Gudmar, Janssen, Sarah F., Luo, Xiaoyan, Ramdas, Wishal D., Vithana, Eranga, Nongpiur, Monisha E., Montgomery, Grant W., Xu, Liang, Mountain, Jenny E., Gharahkhani, Puya, Lu, Yi, Amin, Najaf, Karssen, Lennart C., Sim, Kar-Seng, van Leeuwen, Elisabeth M., Iglesias, Adriana I., Verhoeven, Virginie J. M., Hauser, Michael A., Loon, Seng-Chee, Despriet, Dominiek D. G., Nag, Abhishek, Venturini, Cristina, Sanfilippo, Paul G., Schillert, Arne, Kang, Jae H., Landers, John, Jonasson, Fridbert, Cree, Angela J., van Koolwijk, Leonieke M. E., Rivadeneira, Fernando, Souzeau, Emmanuelle, Jonsson, Vesteinn, Menon, Geeta, Weinreb, Robert N., de Jong, Paulus T. V. M., Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Ennis, Sarah, Thorsteinsdottir, Unnur, Burdon, Kathryn P., Spector, Timothy D., Mirshahi, Alireza, Saw, Seang-Mei, Vingerling, Johannes R., Teo, Yik-Ying, Haines, Jonathan L., Wolfs, Roger C. W., Lemij, Hans G., Tai, E-Shyong, Jansonius, Nomdo M., Jonas, Jost B., Cheng, Ching-Yu, Aung, Tin, Viswanathan, Ananth C., Klaver, Caroline C. W., Craig, Jamie E., Macgregor, Stuart, Mackey, David A., Lotery, Andrew J., Stefansson, Kari, Bergen, Arthur A. B., Young, Terri L., Wiggs, Janey L., Pfeiffer, Norbert, Wong, Tien-Yin, Pasquale, Louis R., Hewitt, Alex W., van Duijn, Cornelia M., Hammond, Christopher J.
Foilsithe 2014

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

le Springelkamp, Henriët, Iglesias, Adriana I., Mishra, Aniket, Höhn, René, Wojciechowski, Robert, Khawaja, Anthony P., Nag, Abhishek, Wang, Ya Xing, Wang, Jie Jin, Cuellar-Partida, Gabriel, Gibson, Jane, Bailey, Jessica N. Cooke, Vithana, Eranga N., Gharahkhani, Puya, Boutin, Thibaud, Ramdas, Wishal D., Zeller, Tanja, Luben, Robert N., Yonova-Doing, Ekaterina, Viswanathan, Ananth C., Yazar, Seyhan, Cree, Angela J., Haines, Jonathan L., Koh, Jia Yu, Souzeau, Emmanuelle, Wilson, James F., Amin, Najaf, Müller, Christian, Venturini, Cristina, Kearns, Lisa S., Kang, Jae Hee, Tham, Yih Chung, Zhou, Tiger, van Leeuwen, Elisabeth M., Nickels, Stefan, Sanfilippo, Paul, Liao, Jiemin, van der Linde, Herma, Zhao, Wanting, van Koolwijk, Leonieke M.E., Zheng, Li, Rivadeneira, Fernando, Baskaran, Mani, van der Lee, Sven J., Perera, Shamira, de Jong, Paulus T.V.M., Oostra, Ben A., Uitterlinden, André G., Fan, Qiao, Hofman, Albert, Tai, E-Shyong, Vingerling, Johannes R., Sim, Xueling, Wolfs, Roger C.W., Teo, Yik Ying, Lemij, Hans G., Khor, Chiea Chuen, Willemsen, Rob, Lackner, Karl J., Aung, Tin, Jansonius, Nomdo M., Montgomery, Grant, Wild, Philipp S., Young, Terri L., Burdon, Kathryn P., Hysi, Pirro G., Pasquale, Louis R., Wong, Tien Yin, Klaver, Caroline C.W., Hewitt, Alex W., Jonas, Jost B., Mitchell, Paul, Lotery, Andrew J., Foster, Paul J., Vitart, Veronique, Pfeiffer, Norbert, Craig, Jamie E., Mackey, David A., Hammond, Christopher J., Wiggs, Janey L., Cheng, Ching-Yu, van Duijn, Cornelia M., MacGregor, Stuart
Foilsithe in Hum Mol Genet (2017)

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

le Lu, Yi, Vitart, Veronique, Burdon, Kathryn P, Khor, Chiea Chuen, Bykhovskaya, Yelena, Mirshahi, Alireza, Hewitt, Alex W, Koehn, Demelza, Hysi, Pirro G, Ramdas, Wishal D, Zeller, Tanja, Vithana, Eranga N, Cornes, Belinda K, Tay, Wan-Ting, Tai, E Shyong, Cheng, Ching-Yu, Liu, Jianjun, Foo, Jia-Nee, Saw, Seang Mei, Thorleifsson, Gudmar, Stefansson, Kari, Dimasi, David P, Mills, Richard A, Mountain, Jenny, Ang, Wei, Hoehn, René, Verhoeven, Virginie J M, Grus, Franz, Wolfs, Roger, Castagne, Raphaële, Lackner, Karl J, Springelkamp, Henriët, Yang, Jian, Jonasson, Fridbert, Leung, Dexter Y L, Chen, Li J, Tham, Clement C Y, Rudan, Igor, Vatavuk, Zoran, Hayward, Caroline, Gibson, Jane, Cree, Angela J, MacLeod, Alex, Ennis, Sarah, Polasek, Ozren, Campbell, Harry, Wilson, James F, Viswanathan, Ananth C, Fleck, Brian, Li, Xiaohui, Siscovick, David, Taylor, Kent D, Rotter, Jerome I, Yazar, Seyhan, Ulmer, Megan, Li, Jun, Yaspan, Brian L, Ozel, Ayse B, Richards, Julia E, Moroi, Sayoko E, Haines, Jonathan L, Kang, Jae H, Pasquale, Louis R, Allingham, R Rand, Ashley-Koch, Allison, Mitchell, Paul, Wang, Jie Jin, Wright, Alan F, Pennell, Craig, Spector, Timothy D, Young, Terri L, Klaver, Caroline C W, Martin, Nicholas G, Montgomery, Grant W, Anderson, Michael G, Aung, Tin, Willoughby, Colin E, Wiggs, Janey L, Pang, Chi P, Thorsteinsdottir, Unnur, Lotery, Andrew J, Hammond, Christopher J, van Duijn, Cornelia M, Hauser, Michael A, Rabinowitz, Yaron S, Pfeiffer, Norbert, Mackey, David A, Craig, Jamie E, Macgregor, Stuart, Wong, Tien Y
Foilsithe 2013

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

le Fritsche, Lars G., Igl, Wilmar, Cooke Bailey, Jessica N., Grassmann, Felix, Sengupta, Sebanti, Bragg-Gresham, Jennifer L., Burdon, Kathryn P., Hebbring, Scott J., Wen, Cindy, Gorski, Mathias, Kim, Ivana K., Cho, David, Zack, Donald, Souied, Eric, Scholl, Hendrik P. N., Bala, Elisa, Lee, Kristine E., Hunter, David J., Sardell, Rebecca J., Mitchell, Paul, Merriam, Joanna E., Cipriani, Valentina, Hoffman, Joshua D., Schick, Tina, Lechanteur, Yara T. E., Guymer, Robyn H., Johnson, Matthew P., Jiang, Yingda, Stanton, Chloe M., Buitendijk, Gabriëlle H. S., Zhan, Xiaowei, Kwong, Alan M., Boleda, Alexis, Brooks, Matthew, Gieser, Linn, Ratnapriya, Rinki, Branham, Kari E., Foerster, Johanna R., Heckenlively, John R., Othman, Mohammad I., Vote, Brendan J., Liang, Helena Hai, Souzeau, Emmanuelle, McAllister, Ian L., Isaacs, Timothy, Hall, Janette, Lake, Stewart, Mackey, David A., Constable, Ian J., Craig, Jamie E., Kitchner, Terrie E., Yang, Zhenglin, Su, Zhiguang, Luo, Hongrong, Chen, Daniel, Ouyang, Hong, Flagg, Ken, Lin, Danni, Mao, Guanping, Ferreyra, Henry, Stark, Klaus, von Strachwitz, Claudia N., Wolf, Armin, Brandl, Caroline, Rudolph, Guenther, Olden, Matthias, Morrison, Margaux A., Morgan, Denise J., Schu, Matthew, Ahn, Jeeyun, Silvestri, Giuliana, Tsironi, Evangelia E., Park, Kyu Hyung, Farrer, Lindsay A., Orlin, Anton, Brucker, Alexander, Li, Mingyao, Curcio, Christine, Mohand-Saïd, Saddek, Sahel, José-Alain, Audo, Isabelle, Benchaboune, Mustapha, Cree, Angela J., Rennie, Christina A., Goverdhan, Srinivas V., Grunin, Michelle, Hagbi-Levi, Shira, Campochiaro, Peter, Katsanis, Nicholas, Holz, Frank G., Blond, Frédéric, Blanché, Hélène, Deleuze, Jean-François, Igo, Robert P., Truitt, Barbara, Peachey, Neal S., Meuer, Stacy M., Myers, Chelsea E., Moore, Emily L., Klein, Ronald, Hauser, Michael A., Postel, Eric A., Courtenay, Monique D., Schwartz, Stephen G., Kovach, Jaclyn L., Scott, William K., Liew, Gerald, Tƒan, Ava G., Gopinath, Bamini, Merriam, John C., Smith, R. Theodore, Khan, Jane C., Shahid, Humma, Moore, Anthony T., McGrath, J. Allie, Laux, Reneé, Brantley, Milam A., Agarwal, Anita, Ersoy, Lebriz, Caramoy, Albert, Langmann, Thomas, Saksens, Nicole T. M., de Jong, Eiko K., Hoyng, Carel B., Cain, Melinda S., Richardson, Andrea J., Martin, Tammy M., Blangero, John, Weeks, Daniel E., Dhillon, Bal, van Duijn, Cornelia M., Doheny, Kimberly F., Romm, Jane, Klaver, Caroline C. W., Hayward, Caroline, Gorin, Michael B., Klein, Michael L., Baird, Paul N., den Hollander, Anneke I., Fauser, Sascha, Yates, John R. W., Allikmets, Rando, Wang, Jie Jin, Schaumberg, Debra A., Klein, Barbara E. K., Hagstrom, Stephanie A., Chowers, Itay, Lotery, Andrew J., Léveillard, Thierry, Zhang, Kang, Brilliant, Murray H., Hewitt, Alex W., Swaroop, Anand, Chew, Emily Y., Pericak-Vance, Margaret A., DeAngelis, Margaret, Stambolian, Dwight, Haines, Jonathan L., Iyengar, Sudha K., Weber, Bernhard H. F., Abecasis, Gonçalo R., Heid, Iris M.
Foilsithe in Nat Genet (2015)