Complement factor I and age-related macular degeneration

PURPOSE: The complement system has been implicated in the pathogenesis of age-related macular degeneration (AMD). Complement factor I (CFI) is a serum protease that inhibits all complement pathways. A previous multicenter study identified a single missense CFI mutation (p.Gly119Arg) in 20/3,567 (0.5...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Alexander, Philip, Gibson, Jane, Cree, Angela J., Ennis, Sarah, Lotery, Andrew J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Molecular Vision 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165324/
https://ncbi.nlm.nih.gov/pubmed/25352734
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