Translational Research in Gastrointestinal Oncology: A Focus on Signaling Pathways in Pancreas Cancer

Yazar: Nagathihalli, Nagaraj
Baskı/Yayın Bilgisi 2011

New mechanistic insights into modifiable risk factors that promote pancreatic cancer

Yazar: Srinivasan, Supriya, Dosch, Austin R., Nagathihalli, Nagaraj S.
Yayımlandı Oncotarget (2019)

Emerging targets in pancreatic cancer: epithelial–mesenchymal transition and cancer stem cells

Yazar: Castellanos, Jason A, Merchant, Nipun B, Nagathihalli, Nagaraj S
Baskı/Yayın Bilgisi 2013

Smoking Induces Epithelial-to-Mesenchymal Transition in Non-Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-cadherin

Yazar: Nagathihalli, Nagaraj S., Massion, Pierre P., Gonzalez, Adriana L., Lu, Pengcheng, Datta, Pran K.
Baskı/Yayın Bilgisi 2012

Optical Imaging of Drug-Induced Metabolism Changes in Murine and Human Pancreatic Cancer Organoids Reveals Heterogeneous Drug Response

Yazar: Walsh, Alex J., Castellanos, Jason A., Nagathihalli, Nagaraj S., Merchant, Nipun B., Skala, Melissa C.
Yayımlandı Pancreas (2016)

Smoking attenuates Transforming growth factor-β-mediated tumor suppression function through down-regulation of Smad3 in lung cancer

Yazar: Samanta, Debangshu, Gonzalez, Adriana L., Nagathihalli, Nagaraj, Ye, Fei, Carbone, David P., Datta, Pran K.
Yayımlandı Cancer Prev Res (Phila) (2012)

Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids

Yazar: Nagathihalli, Nagaraj S., Beesetty, Yugandhar, Lee, Wooin, Washington, M. Kay, Chen, Xi, Lockhart, A. Craig, Merchant, Nipun B.
Baskı/Yayın Bilgisi 2014

Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth

Yazar: Messaggio, Fanuel, Mendonsa, Alisha M., Castellanos, Jason, Nagathihalli, Nagaraj S., Gorden, Lee, Merchant, Nipun B., VanSaun, Michael N.
Yayımlandı Oncotarget (2017)

Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

Yazar: Nagathihalli, Nagaraj S., Castellanos, Jason A., VanSaun, Michael N., Dai, Xizi, Ambrose, Mahogany, Guo, Qiaozhi, Xiong, Yanhua, Merchant, Nipun B.
Yayımlandı Oncotarget (2016)

Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells

Yazar: Dosch, Austin R., Dai, Xizi, Gaidarski III, Alexander A., Shi, Chanjuan, Castellanos, Jason A., VanSaun, Michael N., Merchant, Nipun B., Nagathihalli, Nagaraj S.
Yayımlandı Oncotarget (2019)

Stroma secreted IL6 selects for “stem-like” population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways

Yazar: Kesh, Kousik, Garrido, Vanessa T., Dosch, Austin, Durden, Brittany, Gupta, Vineet K., Sharma, Nikita S., Lyle, Michael, Nagathihalli, Nagaraj, Merchant, Nipun, Saluja, Ashok, Banerjee, Sulagna
Yayımlandı Cell Death Dis (2020)

Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer

Yazar: Nagathihalli, Nagaraj S., Castellanos, Jason A., Lamichhane, Purushottam, Messaggio, Fanuel, Shi, Chanjuan, Dai, Xizi, Rai, Priyamvada, Chen, Xi, VanSaun, Michael N., Merchant, Nipun B.
Yayımlandı Cancer Res (2018)

Combined Src/EGFR inhibition targets STAT3 signaling and induces stromal remodeling to improve survival in pancreatic cancer

Yazar: Dosch, Austin R., Dai, Xizi, Reyzer, Michelle L., Mehra, Siddharth, Srinivasan, Supriya, Willobee, Brent A., Kwon, Deukwoo, Kashikar, Nilesh, Caprioli, Richard, Merchant, Nipun B., Nagathihalli, Nagaraj S.
Yayımlandı Mol Cancer Res (2020)

STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer

Yazar: Nagathihalli, Nagaraj S., Castellanos, Jason A., Shi, Chanjuan, Beesetty, Yugandhar, Reyzer, Michelle L., Caprioli, Richard, Chen, Xi, Walsh, Alex J., Skala, Melissa C., Moses, Harold L., Merchant, Nipun B.
Yayımlandı Gastroenterology (2015)

Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer

Yazar: Srinivasan, Supriya, Totiger, Tulasigeri, Shi, Chanjuan, Castellanos, Jason, Lamichhane, Purushottam, Dosch, Austin R., Messaggio, Fanuel, Kashikar, Nilesh, Honnenahally, Kumaraswamy, Ban, Yuguang, Merchant, Nipun B., VanSaun, Michael, Nagathihalli, Nagaraj S.
Yayımlandı Cancer Res (2018)

Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma

Yazar: Willobee, Brent A., Gaidarski, Alexander A., Dosch, Austin R., Castellanos, Jason A., Dai, Xizi, Mehra, Siddharth, Messaggio, Fanuel, Srinivasan, Supriya, VanSaun, Michael N., Nagathihalli, Nagaraj S., Merchant, Nipun B.
Yayımlandı Mol Cancer Ther (2021)

Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue

Yazar: McPherson, Lisa A., Troccoli, Clara I., Ji, Debin, Bowles, Annie E., Gardiner, Makelle L., Mohsen, Michael G., Nagathihalli, Nagaraj S., Nguyen, Dao M., Robbins, David J., Merchant, Nipun B., Kool, Eric T., Rai, Priyamvada, Ford, James M.
Yayımlandı DNA Repair (Amst) (2019)

Urolithin A, a novel natural compound to target PI3K/AKT/mTOR pathway in pancreatic cancer

Yazar: Totiger, Tulasigeri M., Srinivasan, Supriya, Jala, Venkatakrishna R., Lamichhane, Purushottam, Dosch, Austin R., Gaidarski, Alexander A., Joshi, Chandrashekhar, Rangappa, Shobith, Castellanos, Jason, Vemula, Praveen Kumar, Chen, Xi, Kwon, Deukwoo, Kashikar, Nilesh, VanSaun, Michael, Merchant, Nipun B., Nagathihalli, Nagaraj S.
Yayımlandı Mol Cancer Ther (2018)