Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells

Pancreatic ductal adenocarcinoma (PDAC) is a dynamic tumor supported by several stromal elements such as pancreatic stellate cells (PSC). Significant crosstalk exists between PSCs and tumor cells to stimulate oncogenic signaling and malignant progression of PDAC. However, how PSCs activate intercell...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Nagathihalli, Nagaraj S., Castellanos, Jason A., VanSaun, Michael N., Dai, Xizi, Ambrose, Mahogany, Guo, Qiaozhi, Xiong, Yanhua, Merchant, Nipun B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323208/
https://ncbi.nlm.nih.gov/pubmed/27602757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11786
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