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Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth
Obesity is a significant risk factor for pancreatic cancer, harboring a chronic inflammatory condition characterized by dysregulation of the adipokines, leptin and adiponectin, that in turn alter oncogenic signaling pathways. We and others have shown that leptin promotes the proliferation and an inv...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5689616/ https://ncbi.nlm.nih.gov/pubmed/29156726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19905 |
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