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Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth

Obesity is a significant risk factor for pancreatic cancer, harboring a chronic inflammatory condition characterized by dysregulation of the adipokines, leptin and adiponectin, that in turn alter oncogenic signaling pathways. We and others have shown that leptin promotes the proliferation and an inv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Messaggio, Fanuel, Mendonsa, Alisha M., Castellanos, Jason, Nagathihalli, Nagaraj S., Gorden, Lee, Merchant, Nipun B., VanSaun, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689616/
https://ncbi.nlm.nih.gov/pubmed/29156726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19905
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