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Smoking Induces Epithelial-to-Mesenchymal Transition in Non-Small Cell Lung Cancer through HDAC-Mediated Downregulation of E-cadherin

Epidemiological studies have demonstrated that most cases of lung cancers (85-90%) are directly attributable to tobacco smoking. Although association between cigarette smoking and lung cancer is well documented, surprisingly little is known regarding the molecular mechanisms of how smoking is involv...

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Detalhes bibliográficos
Main Authors: Nagathihalli, Nagaraj S., Massion, Pierre P., Gonzalez, Adriana L., Lu, Pengcheng, Datta, Pran K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969334/
https://ncbi.nlm.nih.gov/pubmed/22933707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0107
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