Role of Organic Anion-Transporting Polypeptides (OATPs) in Cancer Therapy

di Thakkar, Nilay, Lockhart, A. Craig, Lee, Wooin
Pubblicato in AAPS J (2015)

High-Resolution Snapshots of Proteasome Inhibitors In Action Revise Inhibition Paradigms and Inspire Next-Generation Inhibitor Design

di Carmony, Kimberly, Lee, Wooin, Kim, Kyung Bo
Pubblicato in Chembiochem (2016)

Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides

di Lee, Wooin, Ha, Jeong-min, Sugiyama, Yuichi
Pubblicato in J Biol Chem (2020)

Inhibitors of the Immunoproteasome: Current Status and Future Directions

di Miller, Zachary, Ao, Lin, Kim, Kyung Bo, Lee, Wooin
Pubblicazione 2013

Next-generation proteasome inhibitors for cancer therapy

di Park, Ji Eun, Miller, Zachary, Jun, Yearin, Lee, Wooin, Kim, Kyung Bo
Pubblicato in Transl Res (2018)

Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

di Nishiyama, Kotaro, Toshimoto, Kota, Lee, Wooin, Ishiguro, Naoki, Bister, Bojan, Sugiyama, Yuichi
Pubblicato in CPT Pharmacometrics Syst Pharmacol (2019)

Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer

di LaFleur, Bonnie, Lee, Wooin, Billhiemer, Dean, Lockhart, Craig, Liu, Junmei, Merchant, Nipun
Pubblicazione 2011

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype‐Guided Dosing of Tamoxifen

di Nakamura, Toshimichi, Toshimoto, Kota, Lee, Wooin, Imamura, Chiyo K., Tanigawara, Yusuke, Sugiyama, Yuichi
Pubblicato in CPT Pharmacometrics Syst Pharmacol (2018)

Sustained delivery of carfilzomib by tannic acid-based nanocapsules helps develop antitumor immunity

di Taha, Maie S., Cresswell, Gregory M., Park, Joonyoung, Lee, Wooin, Ratliff, Timothy L., Yeo, Yoon
Pubblicato in Nano Lett (2019)

Polymer Micelle Formulations of Proteasome Inhibitor Carfilzomib for Improved Metabolic Stability and Anticancer Efficacy in Human Multiple Myeloma and Lung Cancer Cell Lines

di Ao, Lin, Reichel, Derek, Hu, Di, Jeong, Hyunyoung, Kim, Kyung Bo, Bae, Younsoo, Lee, Wooin
Pubblicato in J Pharmacol Exp Ther (2015)

H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth

di Lee, Min Jae, Miller, Zachary, Park, Ji Eun, Bhattarai, Deepak, Lee, Wooin, Kim, Kyung Bo
Pubblicato in Sci Rep (2019)

Expanded Physiologically‐Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion...

di Asaumi, Ryuta, Menzel, Karsten, Lee, Wooin, Nunoya, Ken‐ichi, Imawaka, Haruo, Kusuhara, Hiroyuki, Sugiyama, Yuichi
Pubblicato in CPT Pharmacometrics Syst Pharmacol (2019)

Surface modification of polymer nanoparticles with native albumin for enhancing drug delivery to solid tumors

di Hyun, Hyesun, Park, Joonyoung, Willis, Kiela, Park, Ji Eun, Lyle, L. Tiffany, Lee, Wooin, Yeo, Yoon
Pubblicato in Biomaterials (2018)

Novel Mechanistic Insights into Ectodomain Shedding of EGFR Ligands Amphiregulin and TGF-α: Impact on Gastrointestinal Cancers Driven by Secondary Bile Acids

di Nagathihalli, Nagaraj S., Beesetty, Yugandhar, Lee, Wooin, Washington, M. Kay, Chen, Xi, Lockhart, A. Craig, Merchant, Nipun B.
Pubblicazione 2014

Elucidating the Catalytic Subunit Composition of Distinct Proteasome Subtypes: A Crosslinking Approach Employing Bifunctional Activity-Based Probes

di Carmony, Kimberly Cornish, Sharma, Lalit Kumar, Lee, Do-Min, Park, Ji Eun, Lee, Wooin, Kim, Kyung-Bo
Pubblicato in Chembiochem (2014)

Comprehensive PBPK Model of Rifampicin for Quantitative Prediction of Complex Drug‐Drug Interactions: CYP3A/2C9 Induction and OATP Inhibition Effects

di Asaumi, Ryuta, Toshimoto, Kota, Tobe, Yoshifusa, Hashizume, Kenta, Nunoya, Ken‐ichi, Imawaka, Haruo, Lee, Wooin, Sugiyama, Yuichi
Pubblicato in CPT Pharmacometrics Syst Pharmacol (2018)

A Comparative In Vivo Study of Albumin-Coated Paclitaxel Nanocrystals and Abraxane

di Park, Joonyoung, Park, Ji Eun, Hedrick, Victoria E., Wood, Karl V., Bonham, Connie, Lee, Wooin, Yeo, Yoon
Pubblicato in Small (2018)

Enhancing docetaxel delivery to multidrug-resistant cancer cells with albumin-coated nanocrystals

di Gad, Sheryhan F., Park, Joonyoung, Park, Ji Eun, Fetih, Gihan N., Tous, Sozan S., Lee, Wooin, Yeo, Yoon
Pubblicato in Mol Pharm (2018)

Development of peptide-based reversing agents for P-glycoprotein-mediated resistance to carfilzomib

di Ao, Lin, Wu, Ying, Kim, Donghern, Jang, Eun Ryoung, Kim, Kyunghwa, Lee, Do-min, Kim, Kyung Bo, Lee, Wooin
Pubblicazione 2012

Near-Infrared Activity-Based Fluorescent Probe for LMP7: A Chemical Proteomics Tool for Immunoproteasome in Living Cells

di Sharma, Lalit Kumar, Lee, Na-Ra, Jang, Eun Ryoung, Lei, Beilei, Zhan, Chang-Guo, Lee, Wooin, Kim, Kyung-Bo
Pubblicazione 2012