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Next-generation proteasome inhibitors for cancer therapy

Over two decades ago, the proteasome was considered a risky or even untenable therapeutic target. Today proteasome inhibitors are a mainstay in the treatment of multiple myeloma (MM) and have sales in excess of three billion US dollars annually. More importantly, the availability of proteasome inhib...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Park, Ji Eun, Miller, Zachary, Jun, Yearin, Lee, Wooin, Kim, Kyung Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151281/
https://ncbi.nlm.nih.gov/pubmed/29654740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2018.03.002
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