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Inhibitors of the Immunoproteasome: Current Status and Future Directions

The ubiquitin-proteasome system (UPS) plays a vital role in maintaining protein homeostasis and regulating numerous cellular processes. The proteasome, a multi-protease complex, is the key component of the UPS and has been validated as a therapeutic target by the FDA's approval of bortezomib an...

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Bibliografski detalji
Glavni autori: Miller, Zachary, Ao, Lin, Kim, Kyung Bo, Lee, Wooin
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821965/
https://ncbi.nlm.nih.gov/pubmed/23181576
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