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Current status of poly(ADP-ribose) polymerase inhibitors and future directions

Inhibitors of poly(ADP-ribose) polymerases (PARPs), which play a key role in DNA damage/repair pathways, have been developed as antitumor agents based on the concept of synthetic lethality. Synthetic lethality is the idea that cell death would be efficiently induced by simultaneous loss of function...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Onco Targets Ther
Egile Nagusiak: Ohmoto, Akihiro, Yachida, Shinichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667784/
https://ncbi.nlm.nih.gov/pubmed/29138572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S139336
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