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The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy
The modulation of DNA repair pathways for therapeutic benefit in cancer has now become a reality with the development of poly (ADP-ribose) polymerase inhibitors (PARPi). PARP is involved in single-strand DNA breaks, which in the presence of defective homologous recombination repair lead to double-st...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
SAGE Publications
2011
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210467/ https://ncbi.nlm.nih.gov/pubmed/22084640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834011417039 |
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