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Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma

PURPOSE OF REVIEW: In 2012, two publications revealed a particular sensitivity of Ewing sarcoma cells to the inhibition of poly(ADP-ribose) polymerase (PARP). This review updates the reader on PARP function, the development of PARP inhibitors (PARPi) and the evidence for targeting PARP in Ewing sarc...

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Detalles Bibliográficos
Main Authors: Vormoor, Britta, Curtin, Nicola J.
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059819/
https://ncbi.nlm.nih.gov/pubmed/24840521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000091
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