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Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
PURPOSE OF REVIEW: In 2012, two publications revealed a particular sensitivity of Ewing sarcoma cells to the inhibition of poly(ADP-ribose) polymerase (PARP). This review updates the reader on PARP function, the development of PARP inhibitors (PARPi) and the evidence for targeting PARP in Ewing sarc...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Lippincott Williams & Wilkins
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059819/ https://ncbi.nlm.nih.gov/pubmed/24840521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0000000000000091 |
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