The Poly(ADP-ribose) polymerase inhibitors in pancreatic cancer
Genome instability and mutations are the hallmarks of cancer. Mutations within BRCA genes increase the risk of pancreatic cancer (PC) development. Poly(ADP-ribose) polymerase inhibitors (PARPi) show the synthetic lethality phenomenon in tumoral cells with BRCA mutation and improve outcomes in patien...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Via Medica
2022-02-01
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| Edice: | Nowotwory |
| Témata: | |
| On-line přístup: | https://journals.viamedica.pl/nowotwory_journal_of_oncology/article/view/85394 |
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