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Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics

The year of 2005 was a watershed in the history of poly(ADP-ribose) polymerase (PARP) inhibitors due to the important findings of selective killing in BRCA-deficient cancers by PARP inhibition. The findings made PARP inhibition one of the most promising new therapeutic approaches to cancers, especia...

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Detalhes bibliográficos
Main Authors: He, Jin-xue, Yang, Chun-hao, Miao, Ze-hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002295/
https://ncbi.nlm.nih.gov/pubmed/20676117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.103
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