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Enhancing docetaxel delivery to multidrug-resistant cancer cells with albumin-coated nanocrystals

Intravenous delivery of poorly water-soluble anticancer drugs such as docetaxel (DTX) is challenging due to the low bioavailability and the toxicity related to solubilizing excipients. Colloidal nanoparticles are used as alternative carriers, but low drug loading capacity and circulation instability...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Gad, Sheryhan F., Park, Joonyoung, Park, Ji Eun, Fetih, Gihan N., Tous, Sozan S., Lee, Wooin, Yeo, Yoon
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064681/
https://ncbi.nlm.nih.gov/pubmed/29341617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00783
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