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Polymer Micelle Formulations of Proteasome Inhibitor Carfilzomib for Improved Metabolic Stability and Anticancer Efficacy in Human Multiple Myeloma and Lung Cancer Cell Lines
Carfilzomib (CFZ) is a second-generation proteasome inhibitor drug approved for the treatment of multiple myeloma. Contrary to its excellent antimyeloma activity, CFZ has shown only limited efficacy in patients with solid malignancies. This lack of efficacy has been attributed in part to rapid degra...
সংরক্ষণ করুন:
| প্রকাশিত: | J Pharmacol Exp Ther |
|---|---|
| প্রধান লেখক: | , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613964/ https://ncbi.nlm.nih.gov/pubmed/26311812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.226993 |
| ট্যাগগুলো: |
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