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Smoking attenuates Transforming growth factor-β-mediated tumor suppression function through down-regulation of Smad3 in lung cancer

Epidemiological studies have demonstrated that most cases of lung cancers (85-90%) are directly attributable to cigarette smoking. Although much information has been gained about the effects of cigarette smoking on various signaling pathways causing lung cancer, nothing is known about the effect cig...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Samanta, Debangshu, Gonzalez, Adriana L., Nagathihalli, Nagaraj, Ye, Fei, Carbone, David P., Datta, Pran K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299594/
https://ncbi.nlm.nih.gov/pubmed/22232600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0313
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