Combined Src/EGFR inhibition targets STAT3 signaling and induces stromal remodeling to improve survival in pancreatic cancer

Lack of durable response to cytotoxic chemotherapy is a major contributor to the dismal outcomes seen in pancreatic ductal adenocarcinoma (PDAC). Extensive tumor desmoplasia and poor vascular supply are two predominant characteristics which hinder the delivery of chemotherapeutic drugs into PDAC tum...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Dosch, Austin R., Dai, Xizi, Reyzer, Michelle L., Mehra, Siddharth, Srinivasan, Supriya, Willobee, Brent A., Kwon, Deukwoo, Kashikar, Nilesh, Caprioli, Richard, Merchant, Nipun B., Nagathihalli, Nagaraj S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7127944/
https://ncbi.nlm.nih.gov/pubmed/31949002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0741
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados