The Human Sulfatase 2 Inhibitor 2,4-Disulfonylphenyl-tert-Butylnitrone (OKN-007) has an Antitumor Effect in Hepatocellular Carcinoma Mediated via Suppression of TGFB1/SMAD2 and Hed...

Por Zheng, Xin, Gai, Xiaohong, Han, Shaoshan, Moser, Catherine D., Hu, Chunling, Shire, Abdirashid M., Floyd, Robert A., Roberts, Lewis R.
Publicado em 2012

Additive effect of apicidin and doxorubicin in sulfatase 1 (SULF1)-expressing hepatocellular carcinoma in vitro and in vivo

Por Lai, Jin-Ping, Sandhu, Dalbir S., Moser, Catherine D., Cazanave, Sophie C., Oseini, Abdul M., Shire, Abdirashid M., Shridhar, Viji, Sanderson, Schuyler O., Roberts, Lewis R.
Publicado em 2009

Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors

Por Lai, Jin-Ping, Sandhu, Dalbir S., Yu, Chunrong, Moser, Catherine D., Hu, Chunling, Shire, Abdirashid M., Aderca, Ileana, Murphy, Linda M., Adjei, Alex A., Sanderson, Schuyler, Roberts, Lewis R.
Publicado em 2010

Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling

Por Nakamura, Ikuo, Zakharia, Kais, Banini, Bubu A., Mikhail, Dalia S., Kim, Tae Hyo, Yang, Ju Dong, Moser, Catherine D., Shaleh, Hassan M., Thornburgh, Sarah R., Walters, Ian, Roberts, Lewis R.
Publicado em 2014

Correction: Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling

Por Nakamura, Ikuo, Zakharia, Kais, Banini, Bubu A., Mikhail, Dalia S., Kim, Tae Hyo, Yang, Ju Dong, Moser, Catherine D., Shaleh, Hassan M., Thornburgh, Sarah R., Walters, Ian, Roberts, Lewis R.
Publicado no PLoS One (2015)

Identification of fucosylated Fetuin-A as a potential biomarker for cholangiocarcinoma

Por Betesh, Lucy, Comunale, Mary Ann, Wang, Mengjun, Liang, Hongyan, Hafner, Julie, Karabudak, Aykan, Giama, Nasra H., Moser, Catherine D., Miyoshi, Eiji, Roberts, Lewis R., Block, Timothy M., Mehta, Anand
Publicado no Proteomics Clin Appl (2017)

Methylated Bone Morphogenetic Protein 3 (BMP3) Gene: Evaluation of Tumor Suppressor Function and Biomarker Potential in Biliary Cancer

Por Kisiel, John B, Li, Jia, Zou, Hongzhi, Oseini, Abdul M, Strauss, Benjamin B, Gulaid, Kadra H., Moser, Catherine D, Aderca, Ileana, Ahlquist, David A, Roberts, Lewis R, Shire, Abdirashid M
Publicado em 2013

Restoration of Epigenetically Silenced Sulfatase 1 Expression by 5-Aza-2′-Deoxycytidine Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy-Induced Apoptosis

Por Shire, Abdirashid, Lomberk, Gwen, Lai, Jin-Ping, Zou, Hongzhi, Tsuchiya, Norihiko, Aderca, Ileana, Moser, Catherine D., Gulaid, Kadra H., Oseini, Abdul, Hu, Chunling, Warsame, Omar, Jenkins, Robert B., Roberts, Lewis R.
Publicado no Med Epigenet (2015)

The Utility of Serum Immunoglobulin G4 in Distinguishing Immunoglobulin G4-Associated Cholangitis from Cholangiocarcinoma

Por Oseini, Abdul M., Chaiteerakij, Roongruedee, Shire, Abdirashid M., Ghazale, Amaar, Kaiya, Joseph, Moser, Catherine D., Aderca, Ileana, Mettler, Teresa A., Therneau, Terry M., Zhang, Lizhi, Takahashi, Naoki, Chari, Suresh T., Roberts, Lewis R.
Publicado em 2011

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Por Chaiteerakij, Roongruedee, Juran, Brian D, Aboelsoud, Mohammed M, Harmsen, William S, Moser, Catherine D, Giama, Nasra H, Allotey, Loretta K, Mettler, Teresa A, Baichoo, Esha, Zhang, Xiaodan, Therneau, Terry M, Lazaridis, Konstantinos N, Roberts, Lewis R
Publicado no Cancer Med (2015)

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Por Ding, Xiwei, Chaiteerakij, Roongruedee, Moser, Catherine D., Shaleh, Hassan, Boakye, Jeffrey, Chen, Gang, Ndzengue, Albert, Li, Ying, Zhou, Yanling, Huang, Shengbing, Sinicrope, Frank A., Zou, Xiaoping, Thomas, Melanie B., Smith, Charles D., Roberts, Lewis R.
Publicado no Oncotarget (2016)

Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis

Por Riordan, Jesse D., Keng, Vincent W., Tschida, Barbara R., Scheetz, Todd E., Bell, Jason B., Podetz-Pedersen, Kelly M., Moser, Catherine D., Copeland, Neal G., Jenkins, Nancy A., Roberts, Lewis R., Largaespada, David A., Dupuy, Adam J.
Publicado em 2013

Activation of the TGFβ/SMAD Transcriptional Pathway Underlies a Novel Tumor Promoting Role of Sulfatase1 in Hepatocellular Carcinoma(*)

Por Dhanasekaran, Renumathy, Nakamura, Ikuo, Hu, Chunling, Chen, Gang, Oseini, Abdul M., Seven, Elif Sezin, Miamen, Alexander G, Moser, Catherine D, Zhou, Wei, van Kuppevelt, Toin H., van Deursen, Jan, Mounajjed, Taofic, Fernandez-Zapico, Martin E., Roberts, Lewis R.
Publicado no Hepatology (2015)

The JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX

Por Aderca, Ileana, Moser, Catherine D., Veerasamy, Manivannan, Bani-Hani, Ahmad H., Bonilla-Guerrero, Ruben, Ahmed, Kadra, Shire, Abdirashid, Cazanave, Sophie C., Montoya, Damian P., Mettler, Teresa A., Burgart, Lawrence J., Nagorney, David M., Thibodeau, Stephen N., Cunningham, Julie M., Lai, Jin-Ping, Roberts, Lewis R.
Publicado em 2008

The oncogenic effect of sulfatase 2 (SULF2) in human hepatocellular carcinoma is mediated in part by glypican 3 (GPC3)-dependent Wnt activation

Por Lai, Jin-Ping, Oseini, Abdul M, Moser, Catherine D, Yu, Chunrong, Elsawa, Sherine F, Hu, Chunling, Nakamura, Ikuo, Han, Tao, Aderca, Ileana, Isomoto, Hajime, Garrity-Park, Megan M, Shire, Abdirashid M, Li, Jia, Sanderson, Schuyler O, Adjei, Alex A, Fernandez-Zapico, Martin E, Roberts, Lewis R
Publicado em 2010

Sulfatase 2 Up-Regulates Glypican 3, Promotes Fibroblast Growth Factor Signaling, and Decreases Survival in Hepatocellular Carcinoma

Por Lai, Jin-Ping, Sandhu, Dalbir S., Yu, Chunrong, Han, Tao, Moser, Catherine D., Jackson, Kenard K., Guerrero, Ruben Bonilla, Aderca, Ileana, Isomoto, Hajime, Garrity-Park, Megan M., Zou, Hongzhi, Shire, Abdirashid M., Nagorney, David M., Sanderson, Schuyler O., Adjei, Alex A., Lee, Ju-Seog, Thorgeirsson, Snorri S., Roberts, Lewis R.
Publicado em 2008

The Transcription Factor GLI1 Mediates TGFβ1 Driven EMT in Hepatocellular Carcinoma via a SNAI1-Dependent Mechanism

Por Zheng, Xin, Rumie Vittar, Natalia B., Gai, Xiaohong, Fernandez-Barrena, Maite G., Moser, Catherine D., Hu, Chunling, Almada, Luciana L., McCleary-Wheeler, Angela L., Elsawa, Sherine F., Vrabel, Anne M., Shire, Abdirashid M., Comba, Andrea, Thorgeirsson, Snorri S., Kim, Youngsoo, Liu, Qingguang, Fernandez-Zapico, Martin E., Roberts, Lewis R.
Publicado em 2012

Activation of the Transcription Factor GLI1 by WNT Signaling Underlies the Role of SULFATASE 2 as a Regulator of Tissue Regeneration

Por Nakamura, Ikuo, Fernandez-Barrena, Maite G., Ortiz-Ruiz, Maria C., Almada, Luciana L., Hu, Chunling, Elsawa, Sherine F., Mills, Lisa D., Romecin, Paola A., Gulaid, Kadra H., Moser, Catherine D., Han, Jing-Jing, Vrabel, Anne, Hanse, Eric A., Akogyeram, Nicholas A., Albrecht, Jeffrey H., Monga, Satdarshan P. S., Sanderson, Schuyler O., Prieto, Jesus, Roberts, Lewis R., Fernandez-Zapico, Martin E.
Publicado em 2013

Combinations of Biomarkers and Milan Criteria for Predicting Hepatocellular Carcinoma Recurrence After Liver Transplantation

Por Chaiteerakij, Roongruedee, Zhang, Xiaodan, Addissie, Benyam D., Mohamed, Essa A., Harmsen, William S., Theobald, Paul J., Peters, Brian E., Balsanek, Joseph G., Ward, Melissa M., Giama, Nasra H., Moser, Catherine D., Oseini, Abdul M., Umeda, Naoki, Venkatesh, Sudhakar, Harnois, Denise M., Charlton, Michael R., Yamada, Hiroyuki, Satomura, Shinji, Algeciras-Schimnich, Alicia, Snyder, Melissa R., Therneau, Terry M., Roberts, Lewis R.
Publicado no Liver Transpl (2015)

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein

Por Wang, Yu, Ding, Xiwei, Wang, Shaoqing, Moser, Catherine D., Shaleh, Hassan M., Mohamed, Essa A., Chaiteerakij, Roongruedee, Allotey, Loretta K., Chen, Gang, Miyabe, Katsuyuki, McNulty, Melissa S., Ndzengue, Albert, Knudson, Ryan A., Greipp, Patricia T., Clark, Karl J., Torbenson, Michael S., Kipp, Benjamin R., Zhou, Jie, Barrett, Michael T., Gustafson, Michael P., Alberts, Steven R., Borad, Mitesh J., Roberts, Lewis R.
Publicado no Cancer Lett (2016)