Restoration of Epigenetically Silenced Sulfatase 1 Expression by 5-Aza-2′-Deoxycytidine Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy-Induced Apoptosis

BACKGROUND: Hepatocellular carcinoma (HCC) is the second most frequent cause of cancer death worldwide. Sulfatase 1 (SULF1) functions as a tumor suppressor in HCC cell lines in vitro but also has an oncogenic effect in some HCCs in vivo. AIM: The purpose of this study was to examine the mechanisms r...

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Detalhes bibliográficos
Publicado no:Med Epigenet
Main Authors: Shire, Abdirashid, Lomberk, Gwen, Lai, Jin-Ping, Zou, Hongzhi, Tsuchiya, Norihiko, Aderca, Ileana, Moser, Catherine D., Gulaid, Kadra H., Oseini, Abdul, Hu, Chunling, Warsame, Omar, Jenkins, Robert B., Roberts, Lewis R.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520440/
https://ncbi.nlm.nih.gov/pubmed/26236329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000375461
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