Additive effect of apicidin and doxorubicin in sulfatase 1 (SULF1)-expressing hepatocellular carcinoma in vitro and in vivo

BACKGROUND/AIMS: There are limited chemotherapy options for hepatocellular carcinoma (HCC). The heparin-degrading endosulfatase SULF1 functions as a liver tumor suppressor. We investigated the effects of the histone deacetylase inhibitor apicidin in combination with doxorubicin in SULF1-expressing H...

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Autors principals: Lai, Jin-Ping, Sandhu, Dalbir S., Moser, Catherine D., Cazanave, Sophie C., Oseini, Abdul M., Shire, Abdirashid M., Shridhar, Viji, Sanderson, Schuyler O., Roberts, Lewis R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756527/
https://ncbi.nlm.nih.gov/pubmed/19376607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2008.12.031
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