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Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets

Cholangiocarcinomas (CCs) are highly lethal malignant tumours arising from the biliary tract epithelium. The disease is notoriously difficult to diagnose and is usually fatal because of its typically late clinical presentation and the lack of effective non-surgical therapeutic modalities. The overal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sandhu, Dalbir S., Shire, Abdirashid M., Roberts, Lewis R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904912/
https://ncbi.nlm.nih.gov/pubmed/18031477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2007.01624.x
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