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Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets

Cholangiocarcinomas (CCs) are highly lethal malignant tumours arising from the biliary tract epithelium. The disease is notoriously difficult to diagnose and is usually fatal because of its typically late clinical presentation and the lack of effective non-surgical therapeutic modalities. The overal...

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Detalhes bibliográficos
Main Authors: Sandhu, Dalbir S., Shire, Abdirashid M., Roberts, Lewis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904912/
https://ncbi.nlm.nih.gov/pubmed/18031477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2007.01624.x
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