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Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targets

Cholangiocarcinomas (CCs) are highly lethal malignant tumours arising from the biliary tract epithelium. The disease is notoriously difficult to diagnose and is usually fatal because of its typically late clinical presentation and the lack of effective non-surgical therapeutic modalities. The overal...

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Main Authors: Sandhu, Dalbir S., Shire, Abdirashid M., Roberts, Lewis R.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904912/
https://ncbi.nlm.nih.gov/pubmed/18031477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2007.01624.x
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