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The Tumor Suppressor Function of Human Sulfatase 1 (SULF1) in Carcinogenesis

Human sulfatase 1 (SULF1) was recently identified and shown to desulfate cellular heparan sulfate proteoglycans (HSPGs). Since sulfated HSPGs serve as co-receptors for many growth factors and cytokines, SULF1 was predicted to modulate growth factor and cytokine signaling. The role of SULF1 in growth...

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Detalles Bibliográficos
Main Authors: Lai, Jin-Ping, Sandhu, Dalbir S., Shire, Abdirashid M., Roberts, Lewis R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925118/
https://ncbi.nlm.nih.gov/pubmed/19373441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12029-009-9058-y
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