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Heparin-Degrading Sulfatases in Hepatocellular Carcinoma: Potential roles in Pathogenesis and Identification of Therapeutic Targets

Hepatocellular carcinoma (HCC) is often diagnosed at an advanced stage for which there are limited treatment options. Two recently identified human heparin-degrading endosulfatases, named sulfatase 1 (SULF1) and sulfatase 2 (SULF2), have been found to be involved in liver carcinogenesis. SULF1 and S...

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Библиографические подробности
Главные авторы: Lai, Jin-Ping, Thompson, James R., Sandhu, Dalbir S., Roberts, Lewis R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042146/
https://ncbi.nlm.nih.gov/pubmed/19086847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796694.4.6.803
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