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Heparin-Degrading Sulfatases in Hepatocellular Carcinoma: Potential roles in Pathogenesis and Identification of Therapeutic Targets

Hepatocellular carcinoma (HCC) is often diagnosed at an advanced stage for which there are limited treatment options. Two recently identified human heparin-degrading endosulfatases, named sulfatase 1 (SULF1) and sulfatase 2 (SULF2), have been found to be involved in liver carcinogenesis. SULF1 and S...

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Autors principals: Lai, Jin-Ping, Thompson, James R., Sandhu, Dalbir S., Roberts, Lewis R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042146/
https://ncbi.nlm.nih.gov/pubmed/19086847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796694.4.6.803
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