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Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein
Cholangiocarcinoma is a highly lethal cancer with limited therapeutic options. Recent genomic analysis of cholangiocarcinoma has revealed the presence of fibroblast growth factor receptor 2 (FGFR2) fusion proteins in up to 13% of intrahepatic cholangiocarcinoma (iCCA). FGFR fusions have been identif...
Gorde:
Argitaratua izan da: | Cancer Lett |
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Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119950/ https://ncbi.nlm.nih.gov/pubmed/27216979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.05.017 |
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